16201

タンニン酸

puriss., powder

• 別名: ガロタンニン, タンニン
• 実験式（ヒル表記法）: C₇₆H₅₂O₄₆
• CAS番号: 1401-55-4
• 分子量: 1701.20
• Beilstein: 8186396
• EC Number: 215-753-2
• MDL番号: MFCD00066397
• UNSPSCコード: 12352106
• PubChem Substance ID: 329751144
• NACRES: NA.21

特性

• グレード: puriss.
• 品質水準: 200
• 形状: powder
• 自己発火温度: 980 °F
• 品質: meets analytical specification of USP
• 不純物: dextrines, gum matters, in accordance; resinous matters, in accordance
• 強熱残分: ≤0.1% (as SO₄)
• 損失: ≤9% loss on drying, 105 °C, 2 h
• mp: 218 °C (lit.)
• 溶解性: H₂O: soluble 1 gm in 0.35ml; glycerol: soluble 1gm in 1 ml (warm); acetone: very soluble; alcohol: freely soluble (Diluted); alcohol: slightly soluble (Dehydrated); alcohol: very soluble; benzene: insoluble; carbon disulfide: insoluble; carbon tetrachloride: insoluble; chloroform: insoluble; diethyl ether: insoluble; hexane: insoluble; petroleum ether: insoluble
• アプリケーション: metabolomics; vitamins, nutraceuticals, and natural products
• SMILES記法: Oc1cc(cc(O)c1O)C(=O)Oc2cc(cc(O)c2O)C(=O)OC[C@H]3O[C@@H](OC(=O)c4cc(O)c(O)c(OC(=O)c5cc(O)c(O)c(O)c5)c4)[C@H](OC(=O)c6cc(O)c(O)c(OC(=O)c7cc(O)c(O)c(O)c7)c6)[C@@H](OC(=O)c8cc(O)c(O)c(OC(=O)c9cc(O)c(O)c(O)c9)c8)[C@@H]3OC(=O)c%10cc(O)c(O)c(OC(=O)c%11cc(O)c(O)c(O)c%11)c%10
• InChI: 1S/C76H52O46/c77-32-1-22(2-33(78)53(32)92)67(103)113-47-16-27(11-42(87)58(47)97)66(102)112-21-52-63(119-72(108)28-12-43(88)59(98)48(17-28)114-68(104)23-3-34(79)54(93)35(80)4-23)64(120-73(109)29-13-44(89)60(99)49(18-29)115-69(105)24-5-36(81)55(94)37(82)6-24)65(121-74(110)30-14-45(90)61(100)50(19-30)116-70(106)25-7-38(83)56(95)39(84)8-25)76(118-52)122-75(111)31-15-46(91)62(101)51(20-31)117-71(107)26-9-40(85)57(96)41(86)10-26/h1-20,52,63-65,76-101H,21H2/t52-,63-,64+,65-,76+/m1/s1
• InChI Key: LRBQNJMCXXYXIU-PPKXGCFTSA-N

詳細

詳細

Tannic acid is the simplest hydrolyzable tannin. The chemical structure of tannic acid has a glucose molecule in its core connected to 10 galloyls groups via aliphatic ester bonds. TA is one of the most abundant natural polyphenols, which can be colorless to yellow in color, and of astringent taste. It can be sourced from the bark of oak, chestnut, hemlock, mangrove, etc.

アプリケーション

Tannic acid has been used:

• as a reference standard to measure the total hydrolyzable tannins in Oak root bark tannin-methanol extract using a UV/Vis spectrophotometer
• as a blood-brain barrier (BBB) impermeable, transcytosis-inhibiting drug in spheroid culture medium
• as a flushing agent to test its effects on metal ions, total organic carbon, and organic matter of soil
• as an inhibitor of free ovalbumin (OVA) uptake by the endocytic mechanism on dendritic cells

生物化学的／生理学的作用

Tannic acid has many pharmacological properties such as antioxidant, anti-inflammatory, antimicrobial, and anti-tumor effects. It also exerts anti-aging, wound healing, and neuroprotective activities. TA is traditionally used as a tanning agent in the food, leather, adhesive, and pharmaceutical industries. It is a natural crosslinker that is useful in building polymeric networks and can be used to design biomedical hydrogels.

安全性情報

• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 2
• 引火点(°F): 390.2 °F
• 引火点(℃): 199 °C