おすすめの製品
由来生物
rabbit
品質水準
結合体
unconjugated
抗体製品の状態
affinity isolated antibody
抗体製品タイプ
primary antibodies
クローン
polyclonal
形状
buffered aqueous solution
分子量
33 kDa
化学種の反応性
dog, guinea pig, human, horse, sheep, bovine, rat
濃度
0.5 mg - 1 mg/mL
テクニック
western blot: suitable
NCBIアクセッション番号
UniProtアクセッション番号
輸送温度
wet ice
保管温度
−20°C
ターゲットの翻訳後修飾
unmodified
遺伝子情報
human ... ACVR2B(93)
免疫原
Synthetic peptide directed towards the C terminal region of human ACVR2B
アプリケーション
Anti-ACVR2B antibody produced in rabbit is suitable for western blotting at a concentration of 0.25μg/ml.
生物化学的／生理学的作用
Activin A receptor, type IIB (ACVR2B) binds activin ligands that promote growth and differentiation via the TGF-β signaling. ACVR2B is expressed in adult hypothalamus and forebrain. Activin receptors IIA and IIB may regulate germ cell proliferation in the human ovary during primordial follicle formation and in mouse testis.
シーケンス
Synthetic peptide located within the following region: HDAEARLSAGCVEERVSLIRRSVNGTTSDCLVSLVTSVTNVDLPPKESSI
物理的形状
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
免責事項
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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保管分類コード
10 - Combustible liquids
WGK
WGK 3
引火点(°F)
Not applicable
引火点(℃)
Not applicable
適用法令
試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。
Jan Code
AV45043-50UG:
AV45043-100UL:
試験成績書（COA）
製品のロット番号・バッチ番号を入力して、試験成績書（COA） を検索できます。ロット番号・バッチ番号は、製品ラベルに「Lot」または「Batch」に続いて記載されています。
Sirisha H S Mendis et al.
Biology of reproduction, 84(2), 379-391 (2010-10-12)
Activin affects many aspects of cellular development, including those essential for reproductive fitness. This study examined the contribution of activin A to murine fetal testicular development, revealing contrasting outcomes of activin actions on Sertoli cells and gonocytes. Shortly after sex
M C Miller et al.
Journal of neuroendocrinology, 24(6), 962-972 (2012-02-03)
The inhibin/activin family of proteins is known to have a broad distribution of synthesis and expression in many species, as well as a variety of functions in reproductive and other physiological systems. Yet, our knowledge regarding the production and function
Se-Jin Lee et al.
Proceedings of the National Academy of Sciences of the United States of America, 102(50), 18117-18122 (2005-12-07)
Myostatin is a secreted protein that normally functions as a negative regulator of muscle growth. Agents capable of blocking the myostatin signaling pathway could have important applications for treating human muscle degenerative diseases as well as for enhancing livestock production.
Varuna C Banduseela et al.
Physiological genomics, 45(12), 477-486 (2013-04-11)
Critical illness myopathy (CIM) is characterized by a preferential loss of the motor protein myosin, muscle wasting, and impaired muscle function in critically ill intensive care unit (ICU) patients. CIM is associated with severe morbidity and mortality and has a
S J Martins da Silva et al.
Developmental biology, 266(2), 334-345 (2004-01-24)
The formation of the essential functional unit of the ovary, the primordial follicle, occurs during fetal life in humans. Factors regulating oogonial proliferation and interaction with somatic cells before primordial follicle formation are largely unknown. We have investigated the expression
ライフサイエンス、有機合成、材料科学、クロマトグラフィー、分析など、あらゆる分野の研究に経験のあるメンバーがおります。.
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