G0424

コリラギン

• 実験式（ヒル表記法）: C₂₇H₂₂O₁₈
• CAS番号: 23094-69-1
• 分子量: 634.45
• MDL番号: MFCD00238565
• UNSPSCコード: 12352205
• PubChem Substance ID: 329799812
• NACRES: NA.25

特性

• アッセイ: ≥98% (HPLC)
• 品質水準: 200
• 形状: powder
• 溶解性: H₂O: 1 mg/mL, clear, colorless
• アプリケーション: metabolomics; vitamins, nutraceuticals, and natural products
• 保管温度: 2-8°C
• SMILES記法: O[C@@H]1[C@H]2COC(=O)c3cc(O)c(O)c(O)c3-c4c(O)c(O)c(O)cc4C(=O)O[C@@H]1[C@@H](O)[C@@H](O2)OC(=O)c5cc(O)c(O)c(O)c5
• InChI: 1S/C27H22O18/c28-9-1-6(2-10(29)16(9)32)24(39)45-27-22(38)23-19(35)13(43-27)5-42-25(40)7-3-11(30)17(33)20(36)14(7)15-8(26(41)44-23)4-12(31)18(34)21(15)37/h1-4,13,19,22-23,27-38H,5H2/t13-,19-,22-,23+,27+/m1/s1
• InChI Key: TUSDEZXZIZRFGC-XIGLUPEJSA-N

詳細

詳細

Corilagin is a polyphenolic tannic acid and a major bioactive compound present in various plant species. It is an active component of Phyllanthus urinaria and Terminalia catappa L extract used to treat various ailments.

アプリケーション

Corilagin has been used to study its inhibitory effect on the growth of breast cancer by inducing apoptosis and autophagy regulated by the release of reactive oxygen species.

生物化学的／生理学的作用

Corilagin shows a variety of biological activities such as anti-inflammatory, anti-viral, anti-oxidant, hepatoprotective, antibacterial, anti-coagulant, hypolipemic and hypotensive. It has been noted to possess anti-tumor, antiproliferative, apoptotic, and autophagic abilities as well. Corilagin has been found to reduce the minimum inhibitory concentration (MIC) of β-lactams against Methicillin-resistant Staphylococcus aureus (MRSA).

Corilagin is a polyphenol, specifically a hydrolyzable tannin, found in Traditional Chinese Medicine herbal preparations. It is reported to have anti-inflammatory and anti-tumor activities.

安全性情報

• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable