PLA0277

Rabbit anti-Cul1 Antibody, Affinity Purified

Powered by Bethyl Laboratories, Inc.

• 別名: CUL-1, Protein YL-1
• UNSPSCコード: 12352203
• NACRES: NA.41
• 化学種の反応性: human, mouse
• application: IP; WB
• テクニック: immunoprecipitation (IP): 2-10 μg/mg; western blot: 1:2,000- 1:10,000

特性

• 由来生物: rabbit
• 品質水準: 100
• 抗体製品の状態: affinity purified immunoglobulin
• 抗体製品タイプ: primary antibodies
• グレード: Powered by Bethyl Laboratories, Inc.
• 化学種の反応性: human, mouse
• テクニック: immunoprecipitation (IP): 2-10 μg/mg; western blot: 1:2,000- 1:10,000
• アクセッション番号: NP_003583.2
• UniProtアクセッション番号: Q13616
• 輸送温度: wet ice
• 保管温度: 2-8°C
• ターゲットの翻訳後修飾: unmodified
• 遺伝子情報: rabbit ... Cul1(8454)

詳細

免疫原

The epitope recognized by PLA0277 maps to a region between residue 726 and 776 of human Cullin 1 using the numbering given in entry NP_003583.2 (GeneID 8454).

物理的形状

トリスクエン酸／リン酸塩緩衝液、pH 7～8、0.09％ アジ化ナトリウム含有

その他情報

Cullin 1 (Cul1) is the core component of multiple cullin-RING-based SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination of proteins involved in cell cycle progression, signal transduction and transcription. In the SCF complex, Cul1 serves as a rigid scaffold that organizes the SKP1-F-box protein and RBX1 subunits. Cul1 may contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q13616]

免責事項

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全性情報

• 保管分類コード: 12 - Non Combustible Liquids
• WGK: nwg
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable