SAB2700730

Monoclonal Anti-TET1 antibody produced in mouse

clone GT1462, affinity isolated antibody, buffered aqueous solution

• 別名: CXXC6, FLJ10839, FLJ41442, TET1
• UNSPSCコード: 12352203
• NACRES: NA.41
• 結合体: unconjugated
• application: ChIP; IF; IHC; IP; WB
• クローン: GT1462, monoclonal
• 化学種の反応性: human, mouse
• citations: 10
• テクニック: ChIP: suitable; immunofluorescence: suitable; immunohistochemistry: 1:100-1:1000; immunoprecipitation (IP): suitable; western blot: 500-3000

特性

• 由来生物: mouse
• 品質水準: 100
• 結合体: unconjugated
• 抗体製品の状態: affinity isolated antibody
• 抗体製品タイプ: primary antibodies
• クローン: GT1462, monoclonal
• フォーム: buffered aqueous solution
• 化学種の反応性: human, mouse
• テクニック: ChIP: suitable; immunofluorescence: suitable; immunohistochemistry: 1:100-1:1000; immunoprecipitation (IP): suitable; western blot: 500-3000
• アイソタイプ: IgG2
• NCBIアクセッション番号: NP_085128
• UniProtアクセッション番号: Q8NFU7
• 輸送温度: wet ice
• 保管温度: −20°C
• ターゲットの翻訳後修飾: unmodified
• 遺伝子情報: human ... TET1(80312)

詳細

詳細

Tet methylcytosine dioxygenase 1 (TET1) is a protein that belongs to the TET family and contains a zinc-binding CXXC domain. It is expressed in embryonic stem cells. The TET1 gene is localized on human chromosome 10q21.3.

アプリケーション

Recombinant protein encompassing a sequence within the center region of human TET1. The exact sequence is proprietary.

Suggested starting dilutions are as follows: ICC/IF: 1:100-1:1000, IHC-P: 1:100-1:1000, IP: 1:100-1:500, WB: 1:500-1:3000, ChIP assay: Assay-dependent dilution. Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the end user.

生物化学的／生理学的作用

Tet methylcytosine dioxygenase 1 (TET1) functions as a 5-methylcytosine (5mC) hydroxylase. It converts 5-methylcytosine to 5-hydroxymethylcytosine, which is crucial for active DNA demethylation in the adult brain. The protein has been linked to the progression of colorectal cancer.

特徴および利点

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

物理的形状

Phosphate-buffered saline, no preservative added.

保管および安定性

Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

その他情報

For in vitro laboratory use only. Not for any clinical, therapeutic or diagnostic use in humans or animals. Not for animal or human consumption.

免責事項

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全性情報

• ピクトグラム: GHS07
• シグナルワード: Warning
• 危険有害性情報: H317,H412
• 注意書き: P261 - P272 - P273 - P280 - P302 + P352 - P333 + P313
• 危険有害性の分類: Aquatic Chronic 3 - Skin Sens. 1
• 保管分類コード: 10 - Combustible liquids
• WGK: WGK 2
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable