SAB2701959

Anti-HMGA2 antibody produced in rabbit

• 別名: HMGI-C, HMGIC, LIPO, STQTL9
• UNSPSCコード: 12352203
• NACRES: NA.41
• クローン: polyclonal
• application: ChIP; IF; IHC (p); IP; WB
• 化学種の反応性: mouse, human, rat
• テクニック: ChIP: suitable; immunofluorescence: suitable; immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable; immunoprecipitation (IP): suitable; western blot: 5000-50000
• citations: 14

特性

• 由来生物: rabbit
• 品質水準: 100
• 結合体: unconjugated
• 抗体製品の状態: purified immunoglobulin
• 抗体製品タイプ: primary antibodies
• クローン: polyclonal
• フォーム: liquid
• 分子量: 12 kDa
• 化学種の反応性: mouse, human, rat
• 濃度: 0.7 mg/mL
• テクニック: ChIP: suitable; immunofluorescence: suitable; immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable; immunoprecipitation (IP): suitable; western blot: 5000-50000
• UniProtアクセッション番号: P52926
• 輸送温度: wet ice
• 保管温度: −20°C
• 遺伝子情報: human ... HMGA2(8091)

詳細

詳細

High mobility group A2 (HMGA2) protein is a non-histone architectural transcription factor. This protein belongs to the high-mobility group adenine/thymine (AT)-hook (HMGA) family. HMGA2 is expressed in the mesenchyme prior differentiation and tumors of epithelial origin. The HMGA2 gene is located on the human chromosome at 12q14.3.

免疫原

Recombinant fragment corresponding to a region within amino acids 1 and 109 of HMGA2 (Uniprot ID#P52926)

アプリケーション

Anti-HMGA2 antibody produced in rabbit has been used in immunohistochemistry (1:250), (1:100), (1:4000).

生物化学的／生理学的作用

High mobility group A2 (HMGA2) protein is involved in regulating the activity of various genes by binding to the adenine/thymine (AT)-rich sequences present in the minor groove of B‑form DNA. This protein plays a role in many biological processes such as the DNA damage repair process, senescence, apoptosis, and cell cycle process. HMGA2 protein also plays a role in epithelial-mesenchymal transition and telomere restoration. Overexpression of HMG2A gene is observed in metastatic lung adenocarcinoma.

特徴および利点

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

物理的形状

1XPBS, 20% Glycerol (pH7). 0.025% ProClin 300 was added as a preservative.

免責事項

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全性情報

• ピクトグラム: GHS07
• シグナルワード: Warning
• 危険有害性情報: H317,H412
• 注意書き: P261 - P272 - P273 - P280 - P302 + P352 - P333 + P313
• 危険有害性の分類: Aquatic Chronic 3 - Skin Sens. 1
• 保管分類コード: 12 - Non Combustible Liquids
• WGK: WGK 2
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable