SAB3500048

Anti-SCARB1 antibody produced in rabbit

affinity isolated antibody, buffered aqueous solution

• 別名: Anti-CD36 and LIMPII analog, Anti-CD36 antigen-like 1, Anti-CLA-1, Anti-SR-BI, Anti-SRB1, Anti-Scavenger receptor class B member 1
• MDL番号: MFCD01634166
• UNSPSCコード: 12352203
• NACRES: NA.41
• 結合体: unconjugated
• application: ELISA; IF; IHC; WB
• クローン: polyclonal
• 化学種の反応性: human, mouse, rat
• citations: 5
• テクニック: ELISA: suitable; immunofluorescence: suitable; immunohistochemistry: suitable; western blot: suitable

特性

• 由来生物: rabbit
• 品質水準: 100
• 結合体: unconjugated
• 抗体製品の状態: affinity isolated antibody
• 抗体製品タイプ: primary antibodies
• クローン: polyclonal
• フォーム: buffered aqueous solution
• 化学種の反応性: human, mouse, rat
• テクニック: ELISA: suitable; immunofluorescence: suitable; immunohistochemistry: suitable; western blot: suitable
• NCBIアクセッション番号: Q8WTV0
• UniProtアクセッション番号: Q8WTV0
• 輸送温度: dry ice
• 保管温度: −20°C
• ターゲットの翻訳後修飾: unmodified
• 遺伝子情報: human ... SCARB1(949)

詳細

詳細

Scavenger receptor class B member 1 (SCARB1), also known as SR-BI, is part of the scavenger receptor superfamily, which is composed of many members with diverse structures, expression patterns, and functions. SCARB1 is a multi-ligand cell-surface receptor that mediates the selective uptake of lipid from HDL cholesterol into cells and is expressed in steroidogenic tissues in adult animals. Other ligands of SCARB1 include native, acetylated, or oxidized LDL and anionic phospholipids. SCARB1-deficient mice have elevated HDL levels and increased susceptibility to atherosclerosis on fat feeding, indicating its importance in the regulation of cholesterol homeostasis. Along with CLDN1, LDL-R, and the tetraspanin superfamily member CD81, SCARB1 has been reported to be an entry factor for the Hepatitis C virus. At least two isoforms of SCARB1 are known to exist.

免疫原

SCARB1 antibody was raised against a 15 amino acid peptide near the amino terminus of human SCARB1.

アプリケーション

Anti-SCARB1 antibody produced in rabbit has been used for immunohistochemistry.

特徴および利点

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

関連事項

The action of this antibody can be blocked using blocking peptide SBP3500048.

物理的形状

約1 mg/mLのPBS (0.02％ アジ化ナトリウム含有)

免責事項

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全性情報

• 保管分類コード: 10 - Combustible liquids
• WGK: WGK 2
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable