SAB4501657
Anti-Keratin 14 antibody produced in rabbit
affinity isolated antibody
別名:
CK-14, Cytokeratin-14, K14, Keratin type I cytoskeletal 14
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すべての画像(3)
About This Item
UNSPSCコード:
12352203
NACRES:
NA.41
結合体:
unconjugated
application:
ELISA
IF
IHC
WB
IF
IHC
WB
クローン:
polyclonal
化学種の反応性:
mouse, human, rat
citations:
6
テクニック:
ELISA: 1:5000
immunofluorescence: 1:100-1:500
immunohistochemistry: 1:50-1:100
western blot: 1:500-1:1000
immunofluorescence: 1:100-1:500
immunohistochemistry: 1:50-1:100
western blot: 1:500-1:1000
おすすめの製品
由来生物
rabbit
品質水準
結合体
unconjugated
抗体製品の状態
affinity isolated antibody
抗体製品タイプ
primary antibodies
クローン
polyclonal
フォーム
buffered aqueous solution
分子量
antigen 51 kDa
化学種の反応性
mouse, human, rat
濃度
~1 mg/mL
テクニック
ELISA: 1:5000
immunofluorescence: 1:100-1:500
immunohistochemistry: 1:50-1:100
western blot: 1:500-1:1000
NCBIアクセッション番号
UniProtアクセッション番号
輸送温度
wet ice
保管温度
−20°C
ターゲットの翻訳後修飾
unmodified
遺伝子情報
human ... KRT14(3861)
詳細
Anti-Keratin 14 Antibody detects endogenous levels of total Keratin 14 protein.
CK14/ KRT14 (keratin 14) is one of the cytokeratin isotypes of human cells. It is the intermediate filament protein, which is the feature of epithelial cells. It is located in human chromosome 17q21.
CK14/ KRT14 (keratin 14) is one of the cytokeratin isotypes of human cells. It is the intermediate filament protein, which is the feature of epithelial cells. It is located in human chromosome 17q21.
免疫原
The antiserum was produced against synthesized peptide derived from human Keratin 14.
Immunogen Range: 1-50
Immunogen Range: 1-50
生物化学的／生理学的作用
CK14/ KRT14 (keratin 14) participates in the collective invasion of salivary adenoid cystic carcinoma (SACC). Mutations in KRT14 results in epidermolysis bullosa simplex.
特徴および利点
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
物理的形状
ウサギIgGのPBS溶液（Mg2+およびCa2+を含まず）、pH 7.4、150 mM NaCl、0.02％ アジ化ナトリウム、50％ グリセロール
免責事項
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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保管分類コード
12 - Non Combustible Liquids
WGK
nwg
引火点(°F)
Not applicable
引火点(℃)
Not applicable
最新バージョンのいずれかを選択してください：
Maree Bilandzic et al.
Cancers, 11(9) (2019-08-25)
Epithelial ovarian cancer metastasis is driven by spheroids, which are heterogeneous cancer cell aggregates released from the primary tumour mass that passively disseminate throughout the peritoneal cavity to promote tumour spread, disease recurrence, and acquired chemoresistance. Despite their clinical importance
Cytokeratin-14 contributes to collective invasion of salivary adenoid cystic carcinoma.
Gao XL, et al.
PLoS ONE, 12(2), e0171341-e0171341 (2017)
KRT14 Haploinsufficiency Results in Increased Susceptibility of Keratinocytes to TNF-?-Induced Apoptosis and Causes Naegeli?Franceschetti?Jadassohn Syndrome.
Lugassy J, et al.
The Journal of Investigative Dermatology, 128(6), 1517-1524 (2008)
Lilian M Fennell et al.
The EMBO journal, 39(24), e103303-e103303 (2020-11-21)
HOIP, the catalytic component of the linear ubiquitin chain assembly complex (LUBAC), is a critical regulator of inflammation. However, how HOIP itself is regulated to control inflammatory responses is unclear. Here, we discover that site-specific ubiquitination of K784 within human
Truong San Phan et al.
Science advances, 7(5) (2021-01-31)
Glucocorticoids (GC), synthesized by the 11β-hydroxylase (Cyp11b1), control excessive inflammation through immunosuppressive actions. The skin was proposed to regulate homeostasis by autonomous GC production in keratinocytes. However, their immunosuppressive capacity and clinical relevance remain unexplored. Here, we demonstrate the potential
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