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![N-(2,3-Dimethyl-5,6,7,8-tetrahydrofuro[2,3-b]quinolin-4-yl)-2-(2-oxo-1-pyrrolidinyl)acetamide](/deepweb/assets/sigmaaldrich/product/structures/911/310/bc1a2cc7-fe3e-441b-9b42-6736df037fa5/640/bc1a2cc7-fe3e-441b-9b42-6736df037fa5.png)
アッセイ
≥98% (HPLC)
フォーム
powder
色
white to beige
溶解性
H2O: 10 mg/mL, clear
保管温度
2-8°C
SMILES記法
[S](=O)(=O)([O-])O.[N+H](C(C)C)(C(C)C)CCNC(=O)CN1CCCC1=O
InChI
1S/C14H27N3O2.H2O4S/c1-11(2)17(12(3)4)9-7-15-13(18)10-16-8-5-6-14(16)19;1-5(2,3)4/h11-12H,5-10H2,1-4H3,(H,15,18);(H2,1,2,3,4)
InChI Key
ACSROKXFXFNERX-UHFFFAOYSA-N
生物化学的／生理学的作用
Pramiracetam is a potent nootropic agent that is a member of the racetam drug family. Pramiracetam improves cognitive deficits associated with traumatic brain injuries. Also, pramiracetam is a specific inhibitor of prolyl endopeptidase.
Pramiracetam is a potent nootropic agent.
Pramiracetam plays an important role in spatial learning and memory in rats. It is considered as a memory enhancing agent and is stronger than piracetam.
特徴および利点
This compound is a featured product for Neuroscience research. Click here to discover more featured Neuroscience products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.
シグナルワード
Warning
危険有害性情報
危険有害性の分類
Acute Tox. 4 Oral
保管分類コード
11 - Combustible Solids
WGK
WGK 3
引火点(°F)
Not applicable
引火点(℃)
Not applicable
適用法令
試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。
Jan Code
SML0816-BULK:
SML0816-VAR:
SML0816-50MG:
SML0816-10MG:
最新バージョンのいずれかを選択してください：
試験成績書（COA）
Lot/Batch Number
A Pavlík et al.
Activitas nervosa superior, 29(1), 62-65 (1987-03-01)
High affinity choline uptake (HACU) in the hippocampus and striatal concentration of dopamine (DA) and homovanillic acid (HVA) as measures of the in vivo acetylcholine and DA turnover, respectively, were estimated in male rats, Long-Evans, following 6-day administration of various
Blockade of the nootropic action of piracetam-like nootropics by adrenalectomy: an effect of dosage?
C Mondadori et al.
Behavioural brain research, 34(1-2), 155-158 (1989-08-01)
The present experiments demonstrate that the absence of any memory-improving action of nootropics in adrenalectomized animals cannot be ascribed to an effect of dosage. Doses of 1, 10, 100, 1000 and 3000 mg/kg p.o. of piracetam, oxiracetam, aniracetam or pramiracetam
Z Fang et al.
Hua xi yi ke da xue xue bao = Journal of West China University of Medical Sciences = Huaxi yike daxue xuebao, 30(4), 411-413 (2001-06-05)
Pharmacokinetic rules of pramiracetam were studied here. After giving pramiracetam orally to dogs, we drew their blood at various times. The drug concentrations in blood plasma were detected by HPLC. 3p87 program was used to calculate the pharmacokinetic parameters. The
A Ennaceur et al.
Behavioural brain research, 33(2), 197-207 (1989-06-01)
The effects of the nootropic drugs Piracetam (Pir) and Pramiracetam (Pram) were evaluated on recognition-memory of rats in a new one-trial test. This test is based on spontaneous exploratory activity and does not involve rule learning or reinforcement. Recognition is
C L Murray et al.
Psychopharmacology, 89(3), 378-381 (1986-01-01)
The effect of the nootropic drug pramiracetam (CI-879) on acquisition of a radial arm maze task was examined in the rat. Two doses of pramiracetam (7.5 mg/kg and 15 mg/kg) were administered daily prior to testing for 7 weeks in
資料
DISCOVER Bioactive Small Molecules for Neuroscience
関連コンテンツ
神経科学分野における低分子生理活性物質の創薬研究
ライフサイエンス、有機合成、材料科学、クロマトグラフィー、分析など、あらゆる分野の研究に経験のあるメンバーがおります。.
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