T6764

トリプロリジン 塩酸塩

≥99%

• 別名: (E)-2-[3-(1-ピロリジニル)-1-p-トリルプロペニル]ピリジン 塩酸塩, trans-2-[3-(1-ピロリジニル)-1-p-トリルプロペニル]ピリジン 塩酸塩
• 実験式（ヒル表記法）: C₁₉H₂₂N₂ · HCl
• CAS番号: 6138-79-0
• 分子量: 314.85
• MDL番号: MFCD00039044
• UNSPSCコード: 12352200
• PubChem Substance ID: 24277808
• NACRES: NA.77

特性

• 品質水準: 200
• アッセイ: ≥99%
• 溶解性: alcohol: soluble 1 in 1.5 of solvent; chloroform: soluble 1 in less than 1 of solvent; H₂O: soluble 50 mg/mL, clear, colorless to yellow
• オーガナイザー: GlaxoSmithKline
• 保管温度: 2-8°C
• SMILES記法: CC(C=C1)=CC=C1/C(C2=NC=CC=C2)=C\CN3CCCC3.Cl
• InChI: 1S/C19H22N2.ClH/c1-16-7-9-17(10-8-16)18(19-6-2-3-12-20-19)11-15-21-13-4-5-14-21;/h2-3,6-12H,4-5,13-15H2,1H3;1H/b18-11+;
• InChI Key: WYUYEJNGHIOFOC-NWBUNABESA-N
• 遺伝子情報: human ... HRH1(3269)

詳細

アプリケーション

Triprolidine has been used as a H1 histaminergic inhibitor to study its effect on long-term potentiation (LTP) in tuberomammillary nucleus (TMN) neurons.

生物化学的／生理学的作用

H₁ヒスタミンレセプタ-アンタゴニスト。

特徴および利点

This compound is featured on the Histamine Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

This compound was developed by GlaxoSmithKline. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

調製ノート

Triprolidine hydrochloride is soluble in water at 50 mg/ml and yields a clear, colorless to yellow solution. It is also soluble in alcohol (1 in 1.5 of solvent) and chloroform (1 in less than 1 of solvent).

安全性情報

• ピクトグラム: GHS07
• シグナルワード: Warning
• 危険有害性情報: H302,H315,H319,H335
• 注意書き: P261 - P264 - P271 - P301 + P312 - P302 + P352 - P305 + P351 + P338
• 危険有害性の分類: Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• ターゲットの組織: Respiratory system
• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 3
• 個人用保護具 (PPE): dust mask type N95 (US), Eyeshields, Gloves