- Lys49 myotoxin from the Brazilian lancehead pit viper elicits pain through regulated ATP release.
Lys49 myotoxin from the Brazilian lancehead pit viper elicits pain through regulated ATP release.
Proceedings of the National Academy of Sciences of the United States of America (2017-03-08)
Chuchu Zhang, Katalin F Medzihradszky, Elda E Sánchez, Allan I Basbaum, David Julius
PMID28265084
要旨
Pain-producing animal venoms contain evolutionarily honed toxins that can be exploited to study and manipulate somatosensory and nociceptive signaling pathways. From a functional screen, we have identified a secreted phospholipase A2 (sPLA2)-like protein, BomoTx, from the Brazilian lancehead pit viper (
材料
製品番号
ブランド
製品内容
Sigma-Aldrich
プロテアーゼ Streptomyces griseus由来, powder, BioReagent, suitable for mouse embryo cell culture, ≥3.5 units/mg solid
Sigma-Aldrich
ProteoMass™チトクロームC MALDI-MSスタンダード, vial of 10 nmol, (M+H+) 12,361.96 Da by calculation
Sigma-Aldrich
ProteoMass™ACTHフラグメント18-39 MALDI-MSスタンダード, vial of 10 nmol, monoisotopic mol wt 2,464.1989 Da
Sigma-Aldrich
ProteoMass™インスリン MALDI-MSスタンダード, vial of 10 nmol, monoisotopic mol wt 5,729.6087 Da
Sigma-Aldrich
ProteoMass™アポミオグロビン MALDI-MSスタンダード, vial of 10 nmol, (M+H+) 16,952.27 Da by calculation