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Merck

STAT6

signal transducer and activator of transcription 6, interleukin-4 induced

동의어:
D12S1644, IL-4-STAT, STAT6B, STAT6C
:
UniProtKB ID:
Clone ID:
  • Human(6778) Summary: The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein plays a central role in exerting IL4 mediated biological responses. It is found to induce the expression of BCL2L1/BCL-X(L), which is responsible for the anti-apoptotic activity of IL4. Knockout studies in mice suggested the roles of this gene in differentiation of T helper 2 (Th2) cells, expression of cell surface markers, and class switch of immunoglobulins. Alternative splicing results in multiple transcript variants.[provided by RefSeq, May 2010]
  • Mouse(20852) signal transducer and activator of transcription 6
  • Rat(362896) signal transducer and activator of transcription 6, interleukin-4 induced
  • domestic cat(101089873) signal transducer and activator of transcription 6, interleukin-4 induced
  • chicken(100859196) signal transducer and activator of transcription 6, interleukin-4 induced
  • dog(100142679) signal transducer and activator of transcription 6, interleukin-4 induced
  • sheep(101102134) signal transducer and activator of transcription 6, interleukin-4 induced
  • cow(353105) signal transducer and activator of transcription 6, interleukin-4 induced
  • Horse(100050053) signal transducer and activator of transcription 6, interleukin-4 induced
  • Zebrafish(337413) signal transducer and activator of transcription 6, interleukin-4 induced
  • domestic guinea pig(100726686) signal transducer and activator of transcription 6, interleukin-4 induced
  • naked mole-rat(101725744) signal transducer and activator of transcription 6, interleukin-4 induced
  • Domestic Rabbit(100344264) signal transducer and activator of transcription 6, interleukin-4 induced

Custom & Knockdown Gene Products

ELISA

제품 번호
설명
Phosphotyrosine STAT6 / Signal Transducer and Activator of Transcription 6 ELISA Kit, ,
human
Cell-Based phospho-STAT ELISA Samper Kit for detecting phospho-STAT1 (pTyr701), phospho-STAT3 (pTyr705), and phospho-STAT5 (pTyr694) in cultured cell lines, 192 assays,
mouse, rat, human

Antibodies

제품 번호
설명
종별 반응성
응용분야
Anti-STAT6 antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
종별 반응성
human
응용분야
immunofluorescence
western blot
Anti-Phospho-STAT6-Y641 antibody produced in rabbit, ,
종별 반응성
human
응용분야
western blot
Anti-phospho STAT6 (Tyr641) Antibody, clone 19E2.1, clone 19E2.1, from mouse,
종별 반응성
human, mouse
응용분야
flow cytometry
western blot
Anti-phospho-STAT6 (Tyr641) Antibody, Upstate®, from rabbit,
종별 반응성
human, mouse
응용분야
western blot
Anti-STAT6 antibody produced in rabbit, affinity isolated antibody, buffered aqueous glycerol solution,
종별 반응성
human
응용분야
immunofluorescence
immunohistochemistry

western blot

Proteins

제품 번호
설명
STAT6, GST tagged human, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
human

esiRNA

제품 번호
설명
MISSION® esiRNA, targeting mouse Stat6,
mouse
MISSION® esiRNA, targeting human STAT6,
human