MABE270

Anti-phospho STAT6 (Tyr641) Antibody, clone 19E2.1

clone 19E2.1, from mouse

• 동의어(들): Signal transducer and activator of transcription 6, IL-4 Stat
• UNSPSC 코드: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

속성

• 생물학적 소스: mouse
• Quality Level: 100
• 항체 형태: purified immunoglobulin
• 항체 생산 유형: primary antibodies
• 클론: 19E2.1, monoclonal
• 종 반응성: human, mouse
• 기술: flow cytometry: suitable; western blot: suitable
• 동형: IgG2aκ
• NCBI 수납 번호: NP_001171549
• UniProt 수납 번호: P42226
• 배송 상태: wet ice
• 타겟 번역 후 변형: phosphorylation (pTyr641)
• 유전자 정보: human ... STAT6(6778)

설명

일반 설명

Signal transducer and activator of transcription 6 (STAT6) transduces signals from extracellular cytokines during adaptive immunity and has recently been found to be important in the innate immune response to viral infection. STAT6 is also involved in the attenuation of the Th1 and Th17 in the nephritogenic immune response. The consequence of STAT6 activity has been associated with the pathogenesis of autoimmune disease and has been found to be actively imported to the nucleus.

특이성

This antibody recognizes STAT6 phosphorylated at (Tyr641).

면역원

Epitope: Phosphorylated (Tyr641)

KLH-conjugated linear peptide corresponding to human STAT6 phosphorylated at (Tyr641).

애플리케이션

Anti-phospho STAT6 (Tyr641) Antibody, clone 19E2.1 is a mouse monoclonal antibody for detection of phospho STAT6 (Tyr641) also known as Signal transducer & activator of transcription 6, IL-4 Stat & has been validated in WB, FC.

Flow Cytometry Analysis: 2 µg/mL from a representative lot detected STAT6 in human peripheral blood leukocytes.

Research Category
Epigenetics & Nuclear Function

Research Sub Category
Transcription Factors

품질

Evaluated by Western Blot in NIH/3T3 cell lysates treated and untreated with PDGF.

Western Blot Analysis: 0.5 µg/mL of this antibody detected STAT6 on 10 µg of PDGF untreated and treated NIH/3T3 cell lysates.

표적 설명

~165 kDa observed

물리적 형태

Format: Purified

Protein G Purified

Purified mouse monoclonal IgG2aκ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

저장 및 안정성

Stable for 1 year at 2-8°C from date of receipt.

분석 메모

Control
NIH/3T3 cell lysates treated and untreated with PDGF

기타 정보

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

안전성 정보

• Storage Class Code: 12 - Non Combustible Liquids
• WGK: WGK 1
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable