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Merck
모든 사진(3)

주요 문서

139351

Sigma-Aldrich

3′-Aminoacetophenone

97%

동의어(들):

3-Acetylaniline

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About This Item

Linear Formula:
H2NC6H4COCH3
CAS Number:
Molecular Weight:
135.16
Beilstein:
386009
EC Number:
MDL number:
UNSPSC 코드:
12352100
PubChem Substance ID:
NACRES:
NA.22

Quality Level

분석

97%

bp

289-290 °C (lit.)

mp

94-98 °C (lit.)

작용기

ketone

SMILES string

CC(=O)c1cccc(N)c1

InChI

1S/C8H9NO/c1-6(10)7-3-2-4-8(9)5-7/h2-5H,9H2,1H3

InChI key

CKQHAYFOPRIUOM-UHFFFAOYSA-N

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일반 설명

3′-Aminoacetophenone acts as bifunctional coupling reagent during the synthesis of pyrimidines.

애플리케이션

3′-Aminoacetophenone (3-Acetylaniline) was used as reagent during the asymmetric total synthesis of pactamycin. It was used as starting reagent during the synthesis of curcumin mimics with substituted sulfonyl group.

픽토그램

Exclamation mark

신호어

Warning

유해 및 위험 성명서

예방조치 성명서

Hazard Classifications

Acute Tox. 4 Oral

Storage Class Code

11 - Combustible Solids

WGK

WGK 2

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

개인 보호 장비

dust mask type N95 (US), Eyeshields, Gloves


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문서 라이브러리 방문

M K Subramanian et al.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 71(1), 59-67 (2008-01-08)
The gas phase infrared spectrum of 3-aminoacetophenone (3AAP) was measured in the range 5000-500 cm(-1) and with a resolution of 0.5 cm(-1). The Fourier transform Raman (FT-Raman) and Fourier transform infrared (FT-IR) spectra of 3AAP were recorded in the solid
Chan Mug Ahn et al.
Bioorganic & medicinal chemistry letters, 19(5), 1481-1483 (2009-01-31)
In order to discover novel small vasodilatory molecules for potential use in the treatment of vascular disease, we tested the vasodilatation effect of two types of synthetic curcumin mimics, amide type (3) and sulfonyl amide type (4), upon the basilar
J S Früchtel et al.
Biotechnology and bioengineering, 71(2), 94-103 (2001-04-05)
A combination of symmetric building blocks and combinatorial functional group transformation for synthesis of pyrimidines was investigated. The purpose of the study was to maximize the return on invested synthetic efforts of reaction development for libraries. A representative set of
Justin T Malinowski et al.
Science (New York, N.Y.), 340(6129), 180-182 (2013-04-13)
Medicinal application of many complex natural products is precluded by the impracticality of their chemical synthesis. Pactamycin, the most structurally intricate aminocyclopentitol antibiotic, displays potent antiproliferative properties across multiple phylogenetic domains, but it is highly cytotoxic. A limited number of

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