149837
2-Ethoxy-1-ethoxycarbonyl-1,2-dihydroquinoline
≥99%, for peptide synthesis
동의어(들):
N-Ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline, EEDQ, Ethyl 1,2-dihydro-2-ethoxyquinoline-1-carboxylate
로그인조직 및 계약 가격 보기
모든 사진(4)
About This Item
실험식(Hill 표기법):
C14H17NO3
CAS Number:
Molecular Weight:
247.29
Beilstein:
533048
EC Number:
MDL number:
UNSPSC 코드:
12352005
PubChem Substance ID:
NACRES:
NA.22
추천 제품
제품명
2-Ethoxy-1-ethoxycarbonyl-1,2-dihydroquinoline, ≥99%
Quality Level
분석
≥99%
양식
solid
반응 적합성
reaction type: Coupling Reactions
mp
62-67 °C (lit.)
응용 분야
peptide synthesis
작용기
ether
저장 온도
2-8°C
SMILES string
CCOC1C=Cc2ccccc2N1C(=O)OCC
InChI
1S/C14H17NO3/c1-3-17-13-10-9-11-7-5-6-8-12(11)15(13)14(16)18-4-2/h5-10,13H,3-4H2,1-2H3
InChI key
GKQLYSROISKDLL-UHFFFAOYSA-N
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일반 설명
2-Ethoxy-1-ethoxycarbonyl-1,2-dihydroquinoline(EEDQ) is a stable, and readily available reagent used to prepare amides and peptides in high yields. At ambient temperature, EEDQ is soluble in an aqueous medium containing organic solvents but insoluble in water. It is used as a coupling agent in peptide synthesis.
애플리케이션
2-Ethoxy-1-ethoxycarbonyl-1,2-dihydroquinoline is used as a coupling agent:
- In the regioselective quaternization of chitosan and its amphiphilic derivatives.
- In the preparation of amide-type S-MA derivative-modified QCM sensors.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
개인 보호 장비
dust mask type N95 (US), Eyeshields, Gloves
이미 열람한 고객
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Neuropharmacology, 33(3-4), 423-431 (1994-03-01)
The effects of N-ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline (EEDQ), an alkylating agent producing irreversible blockade of various membrane bound receptors in brain, were investigated on four different types of serotonin receptors, 5-HT1A, 5-HT1B, 5-HT2A and 5-HT3, in various brain regions in the rat. In
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Two techniques are commonly used to measure antipsychotic induced dopamine D(2) occupancy in animals: competition with a reversible radioligand (3H-raclopride) or with an irreversible receptor inactivator (EEDQ). While both of these techniques have been used in the past, there is
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