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grade
technical
Quality Level
분석
≥95.0% (T)
형태
liquid
density
1.70 g/mL at 20 °C (lit.)
작용기
bromo
ester
ketone
저장 온도
2-8°C
SMILES string
COC(=O)C(=O)CBr
InChI
1S/C4H5BrO3/c1-8-4(7)3(6)2-5/h2H2,1H3
InChI key
MQONVZMIFQQQHA-UHFFFAOYSA-N
일반 설명
Methyl bromopyruvate is an inhibitor of carbonic anhydrase.
애플리케이션
Methyl bromopyruvate was used in the synthesis of 2-(4-amino-4-carboxybutyl)thiazole-4-carboxylic acid and methyl-1-(bromomethyl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-1-carboxylate.
신호어
Warning
유해 및 위험 성명서
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
표적 기관
Respiratory system
Storage Class Code
10 - Combustible liquids
WGK
WGK 3
Flash Point (°F)
257.0 °F - closed cup
Flash Point (°C)
125 °C - closed cup
개인 보호 장비
Eyeshields, Gloves, type ABEK (EN14387) respirator filter
Anne Katrine Kehler et al.
Investigative ophthalmology & visual science, 48(10), 4688-4693 (2007-09-28)
Inhibition of carbonic anhydrase in the eye is an important treatment modality for reducing the intraocular pressure in glaucoma. However, evidence suggests that carbonic anhydrase inhibition also exerts a relaxing effect on the vessels in the optic nerve, and it
Further degradation products of cephalosporin C. Isolation and synthesis of 2-(4-amino-4-carboxybutyl)thiazole-4-carboxylic acid.
J D JEFFERY et al.
The Biochemical journal, 75, 216-223 (1960-05-01)
Pinhong Chen et al.
The Journal of organic chemistry, 74(19), 7533-7535 (2009-09-26)
With chemoselective Dieckmann condensation as the key step, the protective-group-free total synthesis of (+/-)-subincanadine F was accomplished in 7 steps from the commercially available tryptamine in 33% overall yield.
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