추천 제품
Quality Level
분석
99%
형태
solid
mp
176-178 °C (lit.)
solubility
water: soluble 70 mg/mL at 20 °C
작용기
amine
SMILES string
Cc1ccccc1NC(=N)Nc2ccccc2C
InChI
1S/C15H17N3/c1-11-7-3-5-9-13(11)17-15(16)18-14-10-6-4-8-12(14)2/h3-10H,1-2H3,(H3,16,17,18)
InChI key
OPNUROKCUBTKLF-UHFFFAOYSA-N
유전자 정보
human ... EBP(10682)
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일반 설명
1,3-Di-o-tolylguanidine is a selective σ-receptor agonist. 1,3-Di-o-tolylguanidine is σ site ligand and its interaction with dopamine drugs were studied in Wistar rats and Albino Swiss mice.
Zur Mira Azizah Nor Haiza Lah et al.
Journal of pharmaceutical and biomedical analysis, 174, 608-617 (2019-07-03)
A facile electrochemical sandwich immunosensor for the detection of a breast cancer biomarker, the human epidermal growth factor receptor 2 (HER2), was designed, using lead sulfide quantum dots-conjugated secondary HER2 antibody (Ab2-PbS QDs) as a label. Using Ab2-PbS QDs in
Melissa Wares et al.
Antimicrobial agents and chemotherapy, 59(4), 1942-1949 (2015-01-15)
Drug resistance represents a key aspect of human immunodeficiency virus (HIV) treatment failure. It is important to develop nonhuman primate models for studying issues of drug resistance and the persistence and transmission of drug-resistant viruses. However, relatively little work has
Mona Ebadi et al.
Scientific reports, 10(1), 21521-21521 (2020-12-11)
The use of nanocarriers composed of polyethylene glycol- and polyvinyl alcohol-coated vesicles encapsulating active molecules in place of conventional chemotherapy drugs can reduce many of the chemotherapy-associated challenges because of the increased drug concentration at the diseased area in the
Tomokazu Yoshinaga et al.
Antiviral research, 152, 1-9 (2018-02-08)
Cabotegravir (CAB, S/GSK1265744) is an investigational second-generation integrase strand transfer inhibitor (INSTI) with a chemical structure similar to dolutegravir. CAB is under development as a long-acting injectable formulation for treatment of HIV-1 infection and for pre-exposure prophylaxis. We conducted an
Takato Hiranita et al.
Behavioural pharmacology, 22(5-6), 525-530 (2011-08-03)
Previous studies demonstrated the effectiveness of selective σ-receptor (σR) agonists [1,3-di-o-tolylguanidine (DTG), PRE-084] as reinforcers in rats trained to self-administer cocaine. Similar to cocaine, these drugs increased nucleus accumbens shell dopamine levels, and effects of DTG, but not PRE-084, on
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