373605
6,6′-Dithiodinicotinic acid
technical grade, 85%
동의어(들):
Bis[3-Carboxypyridine] 6,6′-disulfide, Bis[3-carboxypyridine] 6,6′-disulfide
로그인조직 및 계약 가격 보기
모든 사진(2)
About This Item
실험식(Hill 표기법):
C12H8N2O4S2
CAS Number:
Molecular Weight:
308.33
EC Number:
MDL number:
UNSPSC 코드:
12352100
PubChem Substance ID:
NACRES:
NA.22
추천 제품
Grade
technical grade
분석
85%
양식
solid
mp
263-265 °C (lit.)
작용기
carboxylic acid
disulfide
SMILES string
OC(=O)c1ccc(SSc2ccc(cn2)C(O)=O)nc1
InChI
1S/C12H8N2O4S2/c15-11(16)7-1-3-9(13-5-7)19-20-10-4-2-8(6-14-10)12(17)18/h1-6H,(H,15,16)(H,17,18)
InChI key
GSASOFRDSIKDSN-UHFFFAOYSA-N
유사한 제품을 찾으십니까? 방문 제품 비교 안내
일반 설명
6,6′-Dithiodinicotinic acid is reported as sulphydryl reagent. 6,6′-Dithiodinicotinic acid is reported to react with thiols, to afford a disulfide and 6-mercaptonicotinic acid. Interaction of 6,6′-dithiodinicotinic acid with the homogenates of Ehrlich ascites cells has been reported.
애플리케이션
6,6′-Dithiodinicotinic acid may be employed as:
- specific thiol blocker to investigate the radioprotective effect of mercaptoethylamine on the thiol level of the outer cell membrane of the Ehrlich ascites tumor cells
- modifier to investigate the polar microenvironment around the reactive Cys283 of rabbit muscle creatine kinase
- dipyridyl-dithio substrate to evaluate the protein disulfide-thiol interchange activity of the auxin stimulated NADH: protein disulfide reductase (NADH oxidase) of soybean plasma membranes
- water-soluble reagent in a study for introducing, in buffered saline, a reactive sulfhydryl group on water-soluble molecules bearing an alkyl-amino group
- chromogen for sulfhydryl groups in the Ellman method for cholinesterase determinations
- spectrophotometric determination of thiols and of total glutathione in human blood
신호어
Warning
유해 및 위험 성명서
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
표적 기관
Respiratory system
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
개인 보호 장비
dust mask type N95 (US), Eyeshields, Gloves
가장 최신 버전 중 하나를 선택하세요:
시험 성적서(COA)
Lot/Batch Number
이미 열람한 고객
P D Dass et al.
Veterinary and human toxicology, 39(1), 11-17 (1997-02-01)
A kinetic analysis of the substitution of 6,6'-dithiodinicotinic acid (DTNA) for 5,5'-dithiobis-2-nitrobenzoic acid (DTNB) for the determination of rat and human erythrocyte acetylcholinesterase (AChE; EC 3.1.1.7) and plasma butyrylcholinesterase (BuChE; EC 3.1.1.8) is presented. Increasing concentrations of DTNB, but not
Metastases limited.
D R Grassetti
Nature, 308(5959), 500-500 (1984-04-05)
M M Konstantinova et al.
Radiobiologiia, 28(3), 364-368 (1988-05-01)
In experiments with Ehrlich ascites tumor cells, using a specific thiol blocker, 6,6'-dithiodinicotinic acid, that does not penetrate the cell and therefore only binds SH-groups of peripheral areas of an external cell membrane, it was demonstrated that (1) the external
J Nandi et al.
The Biochemical journal, 213(3), 587-594 (1983-09-01)
The distribution of free thiol groups associated with the membrane proteins of the purified pig gastric microsomal vesicles was quantified, and the relation of thiol groups to the function of the gastric (H+ + K+)-transporting ATPase system was investigated. Two
The determination of thiols and of total glutathione in human blood using 6,6'-dithiodinicotinic acid (CPDS).
D R Grassetti et al.
Biochemical medicine, 12(2), 149-153 (1975-02-11)
자사의 과학자팀은 생명 과학, 재료 과학, 화학 합성, 크로마토그래피, 분석 및 기타 많은 영역을 포함한 모든 과학 분야에 경험이 있습니다..
고객지원팀으로 연락바랍니다.