391913
(R)-(+)-6-Hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid
98%
동의어(들):
(2R)-3,4-Dihydro-6-hydroxy-2,5,7,8-tetramethyl-2H-1-benzopyran-2-carboxylic acid, (R)-Trolox
로그인조직 및 계약 가격 보기
모든 사진(1)
About This Item
실험식(Hill 표기법):
C14H18O4
CAS Number:
Molecular Weight:
250.29
MDL number:
UNSPSC 코드:
12352005
PubChem Substance ID:
NACRES:
NA.22
추천 제품
Quality Level
분석
98%
양식
solid
광학 활성
[α]27/D +65°, c = 1.2 in ethanol
mp
162 °C (dec.) (lit.)
작용기
carboxylic acid
SMILES string
Cc1c(C)c2O[C@](C)(CCc2c(C)c1O)C(O)=O
InChI
1S/C14H18O4/c1-7-8(2)12-10(9(3)11(7)15)5-6-14(4,18-12)13(16)17/h15H,5-6H2,1-4H3,(H,16,17)/t14-/m1/s1
InChI key
GLEVLJDDWXEYCO-CQSZACIVSA-N
일반 설명
(R)-(+)-6-Hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid, a vitamin E analog, is a mushroom tyrosinase inhibitor.
애플리케이션
(R)-(+)-6-Hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid may be used to incorporate antioxidant property while designing anti-stress agents based on γ-aminobutyric acid (GABA).
신호어
Warning
유해 및 위험 성명서
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
표적 기관
Respiratory system
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
개인 보호 장비
dust mask type N95 (US), Eyeshields, Gloves
이미 열람한 고객
Shyamal Subramanyam et al.
Methods in enzymology, 600, 201-232 (2018-02-21)
Human RAD51 promotes accurate DNA repair by homologous recombination and is involved in protection and repair of damaged DNA replication forks. The active species of RAD51 and related recombinases in all organisms is a nucleoprotein filament assembled on single-stranded DNA
Inhibitory effects of (S)-and (R)-6-hydroxy-2, 5, 7, 8-tetramethylchroman-2-carboxylic acids on tyrosinase activity.
Yu L.
Journal of Agricultural and Food Chemistry, 51(8), 2344-2347 (2003)
Helena Moreira et al.
Acta poloniae pharmaceutica, 74(2), 688-698 (2018-04-07)
Polyphenol rich extracts obtained from cistus herb (Cistus incanus L.) and pomegranate peel (Punica granatum L.) exhibited significant antioxidant activity in V79 cell culture (Chinese hamster lung fibroblasts) -cistus extract reduced intracellular content of reactive oxygen species (ROS) by 30-40%
Novel compounds designed as antistress agents.
Tsiakitzis, KC, et al.
Journal of Medicinal Chemistry, 52(22), 7315-7318 (2009)
Aleksandra Slezak et al.
Acta poloniae pharmaceutica, 74(2), 670-678 (2018-04-07)
Polyphenol rich extracts obtained from cistus herb (Cistus incanus L.) and pomegranate peels (Punica granatunm L.) added at high concentrations (25-100 pg/mL) to V79 (Chinese hamster lung fibroblast) cell cultures, markedly increased intracellular level of ROS (reactive oxygen species). Also
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