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Merck
모든 사진(1)

문서

396788

Sigma-Aldrich

Ethyl formimidate hydrochloride

동의어(들):

Ethyl methanimidate hydrochloride

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About This Item

Linear Formula:
HC(=NH)OC2H5·HCl
CAS Number:
Molecular Weight:
109.55
MDL number:
UNSPSC 코드:
12352100
PubChem Substance ID:
NACRES:
NA.22

형태

solid

mp

75 °C (dec.) (lit.)

저장 온도

2-8°C

SMILES string

Cl.CCOC=N

InChI

1S/C3H7NO.ClH/c1-2-5-3-4;/h3-4H,2H2,1H3;1H

InChI key

JPUTTYRVDANTBN-UHFFFAOYSA-N

일반 설명

Ethyl formimidate hydrochloride is a nitrogen containing organic building block. On heating it undergoes degradation to afford formamidine hydrochloride, ethyl formate and ethyl chloride.

애플리케이션

Ethyl formimidate hydrochloride may be used in the preparation of the following:
  • 5-aminoimidazole-4-carboxylic acid α- and β-ribotides
  • s-triazines
  • 2,3:5,6-di-O-isopropylidene-α- and -β-5-amino-4-ethoxycarbonyl or -carbamoyl-imidazole D-mannofuranosides
  • 5-amino-1-(2-pyridyl)imidazole
Reactant involved in the synthesis of biologically active molecules including:
  • Bredinin via amination of an acyclic precursor
  • Amidine conjugates of the ornithine moiety of an antifungal

Reactant involved in:
  • Intermolecular cyclization
  • Mo-catalyzed asymmetric ring-closing metathesis for synthesis of cyclid amides and amines
  • Synthesis of peptidic 1-cyanopyrrolidines

픽토그램

Exclamation mark

신호어

Warning

유해 및 위험 성명서

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

표적 기관

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

개인 보호 장비

dust mask type N95 (US), Eyeshields, Gloves


시험 성적서(COA)

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문서 라이브러리 방문

Purines, pyrimidines, and imidazoles. XL. A new synthesis of a D-ribofuranosylamine derivative and its use in the synthesis of pyrimidine and imidazole nucleosides.
N J Cusack et al.
Journal of the Chemical Society. Perkin transactions 1, 16, 1720-1731 (1973-01-01)
Purines, pyrimidines, and imidazoles. Part XLI. Glycofuranosylamines derived from D-xylose, D-glucose, D-mannose, and L-rhamnose and their use in the synthesis of pyrimidine and imidazole nucleosides.
Cusack NJ, et al.
Journal of the Chemical Society. Perkin Transactions 1, 73-81 (1974)
Synthesis of the S-Triazine System. Iii. 1 Trimerization of Imidates.
Schaefer FC and Peters GA.
The Journal of Organic Chemistry, 26(8), 2771-2784 (1961)
Rhodd EH and von Richter V.
Chemistry of Organic Compounds: Pt. B. Aliphatic compounds, 551-551 (1951)
Purines, pyrimidines, and imidazoles part 54. Interconversion of some intermediates in the de novo biosynthesis of purine nucleotides.
Cusack NJ, et al.
Journal of the Chemical Society. Perkin Transactions 1, 2316-2321 (1980)

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