409472

N-[3-(Dimethylamino)propyl]methacrylamide

99%, contains MEHQ as inhibitor

• 동의어(들): N ,N -Dimethylaminopropyl methacrylamide, N -[3-(N ,N -Dimethylamino)propyl]methacrylamide
• Linear Formula: H₂C=C(CH₃)CONH(CH₂)₃N(CH₃)₂
• CAS Number: 5205-93-6
• Molecular Weight: 170.25
• EC Number: 226-002-3
• MDL number: MFCD00038359
• UNSPSC 코드: 12162002
• PubChem Substance ID: 24865649
• NACRES: NA.23

속성

• Quality Level: 100
• 설명: contains: ~650ppm MEHQ as inhibitor
• 분석: 99%
• 형태: viscous liquid
• refractive index: n20/D 1.479 (lit.)
• bp: 134 °C/2 mmHg (lit.)
• density: 0.94 g/mL at 25 °C (lit.)
• SMILES string: CN(C)CCCNC(=O)C(C)=C
• InChI: 1S/C9H18N2O/c1-8(2)9(12)10-6-5-7-11(3)4/h1,5-7H2,2-4H3,(H,10,12)
• InChI key: GDFCSMCGLZFNFY-UHFFFAOYSA-N

설명

일반 설명

N-[3-(Dimethylamino)propyl]Methacrylamide (DMAPMA) is a water-soluble methacrylamide monomer. It is highly reactive and can undergo radical polymerization and cross-linking reactions. The presence of methylamino group (-N(CH₃)₂) provides pH responsiveness and hydrophilicity to the resulting polymers. This versatile monomer can be used in drug delivery systems, gene delivery, responsive materials, biocompatible coatings, adhesives, and biomedical engineering.

애플리케이션

• Glucose-containing diblock polycations exhibit molecular weight, charge, and cell-type dependence for pDNA delivery.: This study investigates the use of glucose-containing diblock polycations, including N-[3-(Dimethylamino)propyl]methacrylamide, in pDNA delivery systems. The research demonstrates that the efficiency of pDNA delivery is influenced by the molecular weight and charge of the polycations, as well as the type of cell used. This highlights the potential for tailored gene delivery applications in different cell types, emphasizing the role of N-[3-(Dimethylamino)propyl]methacrylamide in creating biocompatible and effective delivery vectors (Wu et al., 2014).

N-[3-(Dimethylamino)propyl]Methacrylamide can be used:

• As a monomer to synthesize self-healing pH-responsive P(DMAPMA-stat-DAA) hydrogels for drug delivery applications.
• As a cationic monomer to develop gene delivery vector due to its ability to complex with nucleic acids and facilitate their intracellular delivery.
• To fabricate iron oxide nanoparticle formulations for 3D printing. These iron inks are utilized for printing magnetic devices, MRI contrast agents for bioimaging and targeted drug delivery systems.
• To prepare a non-toxic synthetic flocculant for harvesting microalgae.

안전성 정보

• 픽토그램: GHS05,GHS07
• 신호어: Danger
• 유해 및 위험 성명서: H315,H317,H318
• 예방조치 성명서: P280 - P305 + P351 + P338
• Hazard Classifications: Eye Dam. 1 - Skin Irrit. 2 - Skin Sens. 1
• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 1
• Flash Point (°F): 264.2 °F - closed cup
• Flash Point (°C): 129 °C - closed cup
• 개인 보호 장비: Eyeshields, Gloves, type ABEK (EN14387) respirator filter