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Merck
모든 사진(1)

주요 문서

437891

Sigma-Aldrich

Dimethyl chlorophosphate

96%

동의어(들):

Dimethyl phosphorochloridate

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About This Item

Linear Formula:
(CH3O)2P(O)Cl
CAS Number:
Molecular Weight:
144.49
MDL number:
UNSPSC 코드:
12352100
PubChem Substance ID:
NACRES:
NA.22

Quality Level

분석

96%

형태

liquid

refractive index

n20/D 1.413 (lit.)

bp

80 °C/25 mmHg (lit.)

density

1.34 g/mL at 25 °C (lit.)

SMILES string

COP(Cl)(=O)OC

InChI

1S/C2H6ClO3P/c1-5-7(3,4)6-2/h1-2H3

InChI key

NGFFLHMFSINFGB-UHFFFAOYSA-N

애플리케이션

Dimethyl chlorophosphate may be used for the preparation of (E)-3-cyanophosphoenolpyruvate, by reaction with the potassium enolate of ethyl cyanopyruvate. It may be used for the synthesis of mono- and diphosphate esters of 2-arachidonyl glyceryl ether.

픽토그램

Skull and crossbonesCorrosion

신호어

Danger

유해 및 위험 성명서

Hazard Classifications

Acute Tox. 2 Dermal - Acute Tox. 2 Inhalation - Acute Tox. 2 Oral - Eye Dam. 1 - Skin Corr. 1B

Storage Class Code

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

WGK

WGK 3

Flash Point (°F)

235.4 °F - closed cup

Flash Point (°C)

113 °C - closed cup

개인 보호 장비

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter


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시험 성적서(COA)

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문서 라이브러리 방문

Amanda R Wilmsmeyer et al.
Langmuir : the ACS journal of surfaces and colloids, 28(30), 10962-10967 (2012-07-12)
The fundamental interactions of dimethyl methylphosphonate (DMMP) and dimethyl chlorophosphate (DMCP) on amorphous silica nanoparticles have been investigated with transmission infrared spectroscopy and temperature-programmed desorption (TPD). DMMP and DMCP both adsorb molecularly to silica through the formation of hydrogen bonds
Juha Juntunen et al.
Journal of medicinal chemistry, 46(23), 5083-5086 (2003-10-31)
The poor aqueous solubility of 2-arachidonyl glyceryl ether (noladin ether) 2 hinders both pharmacological studies and pharmaceutical development. The synthesized mono- and diphosphate esters of noladin ether (4 and 6) considerably increased the aqueous solubility of noladin ether (>40000-fold), showed
P Wirsching et al.
Biochemistry, 24(26), 7602-7606 (1985-12-17)
(E)-3-Cyanophosphoenolpyruvate has been synthesized by reacting dimethyl chlorophosphate with the potassium enolate of ethyl cyanopyruvate. The resulting trialkyl ester was deesterified with bromotrimethylsilane followed by potassium hydroxide. Subsequent treatment with Dowex-50-H+ resin and cyclohexylamine afforded the tricyclohexylammonium salt; only the
Minji Kang et al.
ACS applied materials & interfaces, 11(8), 7686-7694 (2019-02-16)
Quorum sensing (QS) inhibitor-based therapy is an attractive strategy to inhibit bacterial biofilm formation without excessive induction of antibiotic resistance. Thus, we designed Ca2+-binding poly(lactide- co-glycolide) (PLGA) microparticles that can maintain a sufficient concentration of QS inhibitors around hydroxyapatite (HA)

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