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Merck
모든 사진(1)

주요 문서

474789

Sigma-Aldrich

(S)-(−)-Glycidol

97%, optical purity ee: 98% (GLC)

동의어(들):

(S)-(−)-2,3-Epoxy-1-propanol, (S)-(−)-Oxirane-2-methanol

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About This Item

실험식(Hill 표기법):
C3H6O2
CAS Number:
Molecular Weight:
74.08
Beilstein:
79783
MDL number:
UNSPSC 코드:
12352005
PubChem Substance ID:
NACRES:
NA.22

Quality Level

분석

97%

광학 활성

[α]20/D −15°, neat

광학 순도

ee: 98% (GLC)

refractive index

n20/D 1.433 (lit.)

bp

66-67 °C/19 mmHg (lit.)

density

1.116 g/mL at 20 °C (lit.)

작용기

ether
hydroxyl

저장 온도

−20°C

SMILES string

OC[C@H]1CO1

InChI

1S/C3H6O2/c4-1-3-2-5-3/h3-4H,1-2H2/t3-/m0/s1

InChI key

CTKINSOISVBQLD-VKHMYHEASA-N

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일반 설명

Glycidol or 2,3-epoxy-1-propanol is a highly reactive epoxy derivative, which is generally used as a monomer in the preparation of many polymers like polyesters, polycarbonates, polyurethanes, and polyamides. It is also used in the preparation of detergents, rubbers, perfumes, fabric dyes, varnishes, cosmetics, and paints.

애플리케이션

Employed in the synthesis of chiral (E)-allylic alcohol side-chains for introduction into prostacyclin and prostaglandin frameworks by cross-metathesis.

픽토그램

Skull and crossbonesHealth hazard

신호어

Danger

Hazard Classifications

Acute Tox. 2 Inhalation - Acute Tox. 4 Dermal - Acute Tox. 4 Oral - Carc. 1B - Eye Irrit. 2 - Muta. 2 - Repr. 1B - Skin Irrit. 2 - STOT SE 3

표적 기관

Respiratory system

Storage Class Code

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

WGK

WGK 3

Flash Point (°F)

161.6 °F

Flash Point (°C)

72 °C

개인 보호 장비

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter


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이미 열람한 고객

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Neil A Sheddan et al.
Organic letters, 8(14), 3101-3104 (2006-06-30)
[reaction: see text] A cross metathesis (CM) approach has been successfully applied to introduce fully functionalized omega-side chain appendages of various prostacyclin and prostaglandin analogues, resulting in high (E)-selectivities for the C13-C14 double bond and leading to the total syntheses
One-pot synthesis of glycidol from glycerol and dimethyl carbonate over KF/sepiolite catalyst
Algoufi YT, et al.
Applied Catalysis A: General, 487, 181-188 (2014)
A simplified early stage assessment of process intensification: glycidol as a value-added product from epichlorohydrin industry wastes
Cespi D, et al.
Green Chemistry, 18(16), 4559-4570 (2016)
Nicolas M B Brancucci et al.
Cell, 171(7), 1532-1544 (2017-11-14)
Transmission represents a population bottleneck in the Plasmodium life cycle and a key intervention target of ongoing efforts to eradicate malaria. Sexual differentiation is essential for this process, as only sexual parasites, called gametocytes, are infective to the mosquito vector. Gametocyte production
Troy D Haines et al.
Journal of the American Oil Chemists' Society, 88(1), 1-14 (2011-02-26)
Analysis of MCPD esters and glycidyl esters in vegetable oils using the indirect method proposed by the DGF gave inconsistent results when salting out conditions were varied. Subsequent investigation showed that the method was destroying and reforming MCPD during the

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