855022
Friedelin
technical grade
동의어(들):
(4β,5β,8α,9β,10α,13α,14β)-5,9,13-Trimethyl-24,25,26-trinoroleanan-3-one, DA-friedooleanan-3-one, Friedelan-3-one
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모든 사진(2)
About This Item
실험식(Hill 표기법):
C30H50O
CAS Number:
Molecular Weight:
426.72
Beilstein:
1916451
EC Number:
MDL number:
UNSPSC 코드:
12352115
PubChem Substance ID:
NACRES:
NA.22
추천 제품
Grade
technical grade
Quality Level
양식
solid
mp
262-265 °C (lit.)
작용기
ketone
SMILES string
C[C@H]1C(=O)CC[C@@H]2[C@]1(C)CC[C@H]3[C@@]2(C)CC[C@@]4(C)[C@@H]5CC(C)(C)CC[C@]5(C)CC[C@]34C
InChI
1S/C30H50O/c1-20-21(31)9-10-22-27(20,5)12-11-23-28(22,6)16-18-30(8)24-19-25(2,3)13-14-26(24,4)15-17-29(23,30)7/h20,22-24H,9-19H2,1-8H3/t20-,22+,23-,24+,26+,27+,28-,29+,30-/m0/s1
InChI key
OFMXGFHWLZPCFL-SVRPQWSVSA-N
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일반 설명
Friedelin, a pentacyclic triterpene, is found in several plants like Cissus quadrangularis, Celastrus vulcanicola, Terminalia avicennioides, and Alangium salvifolium. It is known to act as a histamine H1 receptor (H1R) antagonist, anti-microbial, anti-HIV, and anti-cancer agent.
애플리케이션
Friedelin can be used as a starting material in the synthesis of:
- Friedel-3-enol acetate, friedel-2-oxo-3-enol acetate, friedel-2-ene derivatives and friedelin ketoxime.
- Oxygenated friedelin derivatives as potent DNA topoisomerase IIα inhibitors.
- Its 1,4-pyrazine derivatives as potent antimicrobial agents.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
개인 보호 장비
Eyeshields, Gloves, type N95 (US)
가장 최신 버전 중 하나를 선택하세요:
Iridium-catalyzed intermolecular amidation of sp3 C-H bonds: late-stage functionalization of an unactivated methyl group
Kang T, et al.
Journal of the American Chemical Society, 136(11), 4141-4144 (2014)
Ramesh Kumari et al.
Journal of ethnopharmacology, 138(1), 256-259 (2011-09-24)
Commiphora berryi is traditionally used for the treatment of cold and fever as well as for wound healing in the southern parts of India. The present study was designed to investigate in vitro soybean lipoxygenase inhibitory activity of crude extracts
Microwave assisted one-pot synthesis of pyrazine derivatives of pentacyclic triterpenoids and their biological activity
Ghosh P, et al.
Indian J. Chem. B, 50B(11), 1519-1523 (2011)
Synthesis of friedelan triterpenoid analogs with DNA topoisomerase IIα inhibitory activity and their molecular docking studies
Mandal A, et al.
European Journal of Medicinal Chemistry, 54(11), 137-143 (2012)
Effects of 8-Hydroxyisocapnolactone-2-3-diol and friedelin on mast cell degranulation
Sahid MNA, et al.
Asian Pacific Journal of Tropical Medicine, 10(11), 1043-1046 (2017)
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