모든 사진(2)
About This Item
실험식(Hill 표기법):
C11H12N2O5
CAS Number:
Molecular Weight:
252.22
MDL number:
UNSPSC 코드:
12352208
NACRES:
NA.22
추천 제품
Quality Level
분석
95%
양식
powder
mp
206 °C
저장 온도
−20°C
SMILES string
OC[C@@H]1[C@@H](O)C[C@H](N2C(NC(C(C#C)=C2)=O)=O)O1
InChI
1S/C11H12N2O5/c1-2-6-4-13(11(17)12-10(6)16)9-3-7(15)8(5-14)18-9/h1,4,7-9,14-15H,3,5H2,(H,12,16,17)/t7-,8+,9+/m0/s1
InChI key
CDEURGJCGCHYFH-DJLDLDEBSA-N
일반 설명
5-Ethynyl-2′-deoxyuridine (EdU) is a thymidine analogue that can be incorporated into cellular DNA for cell proliferation studies. The incorporated nucleoside analogue can be detected by a copper-catalyzed click reaction with a fluorescent azide.
애플리케이션
5-Ethynyl-2′-deoxyuridine (EdU) is used for:
For a listing of the Baseclick kits see: Baseclick kits
- Labeling newly synthesized DNA during replication
- Cell proliferating assay studies
- Cell cycle analysis
For a listing of the Baseclick kits see: Baseclick kits
신호어
Danger
유해 및 위험 성명서
Hazard Classifications
Muta. 1B - Repr. 2
Storage Class Code
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
이미 열람한 고객
Cell type specific applicability of 5-ethynyl-2?-deoxyuridine (EdU) for dynamic proliferation assessment in flow cytometry
S Diermeier
Cytometry. Part A : the Journal of the International Society For Analytical Cytology, 75, 535-546 (2009)
Synthesis, susceptibility to enzymatic phosphorylation, cytotoxicity and in vitro antiviral activity of lipophilic pyrimidine nucleoside/carborane conjugates.
Bialek-Pietras M, et al.
Journal of Organometallic Chemistry, 865, 166-172 (2018)
Evaluation of 5-ethynyl-2?-deoxyuridine staining as a sensitive and reliable method for studying cell proliferation in the adult nervous system
C Zeng, et.al.
Brain Research, 1319, 21-32 (2010)
5-Ethynyl-2?-deoxycytidine as a new agent for DNA labeling: detection of proliferating cells
D Qu, et.al.
Analytical Biochemistry, 417, 112-121 (2011)
Click chemistry as a reliable method for the high-density postsynthetic functionalization of alkyne-modified DNA.
Gierlich J, et al.
Organic Letters, 8(17), 3639-3642 (2006)
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