모든 사진(2)
About This Item
Linear Formula:
(C2H5N . HCl)n
CAS Number:
MDL number:
UNSPSC 코드:
12162002
NACRES:
NA.23
추천 제품
Quality Level
양식
powder
색상
white to off-white
저장 온도
2-8°C
SMILES string
N(CCC)C
InChI
1S/C4H11N/c1-3-4-5-2/h5H,3-4H2,1-2H3
InChI key
GVWISOJSERXQBM-UHFFFAOYSA-N
애플리케이션
PEI Prime™ is a cationic polymer designed for high-yield, reproducible and scalable drug and gene delivery. As a gene carrier, PEI forms a complex with nucleic acids via electrostatic self-assembly between the negatively charged nucleic acid phosphate groups and positively charged PEI amine groups. Due to this interaction, PEI has been extensively explored as a gene carrier and is one of the most effective synthetic polymers for the delivery of nucleic acids into cells through endocytosis.
PEI Prime™ uses an optimized form of PEI to reduce performance variance and speed process development time. Each batch of PEI Prime™ undergoes triplicate, quantitative performance testing using an SEAP reporter assay. PEI Prime™ is an excellent choice to produce any biologic cost-effectively, including recombinant proteins, antibodies, and viruses.
PEI Prime™ uses an optimized form of PEI to reduce performance variance and speed process development time. Each batch of PEI Prime™ undergoes triplicate, quantitative performance testing using an SEAP reporter assay. PEI Prime™ is an excellent choice to produce any biologic cost-effectively, including recombinant proteins, antibodies, and viruses.
법적 정보
PEI Prime is a trademark of Serochem LLC
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
S M Zou et al.
The journal of gene medicine, 2(2), 128-134 (2000-05-16)
Several nonviral vectors including linear polyethylenimine (L-PEI) confer a pronounced lung tropism to plasmid DNA when injected into the mouse tail vein in a nonionic solution. and results We have optimized this route by injecting 50 microg DNA with excess
L Wightman et al.
The journal of gene medicine, 3(4), 362-372 (2001-09-01)
Efficient gene transfer is a major challenge for non-viral gene therapy. Understanding how non-viral vectors initiate gene expression could lead to the development of new future vectors with enhanced efficacy. Linear or branched polyethylenimine (PEI)/DNA complexes were generated in varying
W T Godbey et al.
Biomaterials, 22(5), 471-480 (2001-02-24)
Poly(ethylenimine) (PEI) was used to transfect the endothelial cell line EA.hy 926, and the secreted levels of three gene products, tissue-type plasminogen activator (tPA), plasminogen activator inhibitor type 1 (PAI-1), and von Willebrand Factor (vWF), were assessed via ELISA. We
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