C88505

Cyanoacetic acid

99%

• 동의어(들): 2-Cyanoacetic acid, Cyanoethanoic acid, Malonic mononitrile, Monocyanoacetic acid
• Linear Formula: NCCH₂COOH
• CAS Number: 372-09-8
• Molecular Weight: 85.06
• Beilstein: 506325
• EC Number: 206-743-9
• MDL number: MFCD00002677
• UNSPSC 코드: 12352100
• PubChem Substance ID: 24893110
• NACRES: NA.22

속성

• vapor pressure: 0.1 mmHg ( 100 °C)
• Quality Level: 100
• 분석: 99%
• 양식: crystals
• bp: 108 °C/0.15 mmHg (lit.)
• mp: 64-70 °C (lit.)
• solubility: H₂O: 50 mg/mL, clear, colorless to very faintly yellow
• SMILES string: OC(=O)CC#N
• InChI: 1S/C3H3NO2/c4-2-1-3(5)6/h1H2,(H,5,6)
• InChI key: MLIREBYILWEBDM-UHFFFAOYSA-N

설명

애플리케이션

Cyanoacetic acid can be used as a reagent:

• Along with acetic anhydride for cyanoacetylation of various pyrroles, indoles, and aniline derivatives. It can also be used in other reactions such as cyclizations, syntheses of coumarins and other heterocycles.
• To prepare of key intermediate via Knoevenagel condensation in the total synthesis of 5-acetamido-substituted melatonin derivatives as MT3 receptor ligands.
• In the synthesis of aminopyrrolinone derivatives by reacting Ugi adducts of cyanoacetic acid and aromatic aldehydes.

안전성 정보

• 픽토그램: GHS05,GHS07
• 신호어: Danger
• 유해 및 위험 성명서: H302 + H332,H314
• 예방조치 성명서: P260 - P280 - P301 + P312 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Dam. 1 - Skin Corr. 1B
• 보충제 위험성: EUH031
• Storage Class Code: 8A - Combustible corrosive hazardous materials
• WGK: WGK 1
• Flash Point (°F): 224.6 °F - closed cup
• Flash Point (°C): 107 °C - closed cup
• 개인 보호 장비: Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges