QBD10260

m-dPEG^®₈-NHS ester

• 동의어(들): 2,5,8,11,14,17,20,23-Octaoxahexacosan-26-oic acid succinimidyl ester, 2,5-Dioxo-1-pyrrolidinyl 4,7,10,13,16,19,22,25-octaoxahexacosanoate, Polyethylene glycol
• 실험식(Hill 표기법): C₂₂H₃₉NO₁₂
• CAS Number: 756525-90-3
• Molecular Weight: 509.54
• MDL number: MFCD13184969
• UNSPSC 코드: 12352108
• PubChem Substance ID: 329823901
• NACRES: NA.22

속성

• 분석: >90%
• 형태: solid or viscous liquid
• 반응 적합성: reagent type: chemical modification reagent; reagent type: cross-linking reagent; reactivity: amine reactive
• 폴리머 구조: shape: linear; functionality: monofunctional
• 배송 상태: ambient
• 저장 온도: −20°C
• SMILES string: O=C(CCOCCOCCOCCOCCOCCOCCOCCOC)ON1C(CCC1=O)=O
• InChI: 1S/C22H39NO12/c1-27-6-7-29-10-11-31-14-15-33-18-19-34-17-16-32-13-12-30-9-8-28-5-4-22(26)35-23-20(24)2-3-21(23)25/h2-19H2,1H3
• InChI key: IBZNTYBFTKFSMU-UHFFFAOYSA-N

설명

특징 및 장점

The m-dPEG^®₈-NHS ester provides a variety of means to modify small molecules, peptides, proteins, and functionalized surfaces (metals, glass, and others). The single molecular weight methoxy-terminated dPEG^® molecules are hydrophilic and non-immunogenic of exact length. Modification with m-dPEG^® reagents can improve water solubility, increase hydrodynamic volume, eliminate or reduce non-specific binding, protect peptides and proteins from proteolysis, reduce or eliminate immunogenicity, and increase serum half-life in vivo. The m-dPEG^®₈-NHS ester reacts with amines.

법적 정보

Products Protected under U.S. Patents # 7,888,536 B2

dPEG is a registered trademark of Quanta BioDesign

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable