QBD10503

Azido-dPEG^®₈-NHS ester

• 동의어(들): 2,5-Dioxo-1-pyrrolidinyl 3-[(23-azido-3,6,9,12,15,18,21-heptaoxatricos-1-yl)oxy]propanoate, Polyethylene glycol
• 실험식(Hill 표기법): C₂₃H₄₀N₄O₁₂
• CAS Number: 1204834-00-3
• Molecular Weight: 564.58
• MDL number: MFCD13184949
• UNSPSC 코드: 12161502
• PubChem Substance ID: 329823932
• NACRES: NA.22

속성

• 분석: >90%
• 형태: solid or viscous liquid
• 반응 적합성: reaction type: click chemistry; reagent type: cross-linking reagent; reaction type: click chemistry
• 작용기: NHS ester; azide
• 폴리머 구조: shape: linear; functionality: heterobifunctional
• 배송 상태: ambient
• 저장 온도: −20°C
• SMILES string: O=C(ON1C(CCC1=O)=O)CCOCCOCCOCCOCCOCCOCCOCCOCCN=[N+]=[N-]

설명

특징 및 장점

The azido-dPEG^®₈-NHS ester contains an azide function on one end of a single molecular weight dPEG^® spacer(32.2 Å) and a reactive group (NHS ester) on the other end of the spacer. The dPEG^® spacer is hydrophilic and non-immunogenic and improves the water solubility of the target molecule while reducing the immunogenicity and increasing the hydrodynamic volume of the target. N-hydroxysuccinimide (NHS) ester readily react with amines in aqueous solution or organic solvent. The azide group reacts with an alkyne in the well-known click chemistry reaction. The click chemistry reaction proceeds by copper(I) or ruthenium catalysis or in a strain-catalyzed reaction with certain types of alkyne partners.

법적 정보

Products Protected under U.S. Patents # 7,888,536 B2

dPEG is a registered trademark of Quanta BioDesign

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable