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Merck
모든 사진(1)

주요 문서

W224502

Sigma-Aldrich

Carvacrol

≥98%, FCC, FG

동의어(들):

5-Isopropyl-2-methylphenol

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About This Item

Linear Formula:
(CH3)2CHC6H3(CH3)OH
CAS Number:
Molecular Weight:
150.22
FEMA Number:
2245
Beilstein:
1860514
EC Number:
유럽평의회 번호:
2055
MDL number:
UNSPSC 코드:
12164502
PubChem Substance ID:
플래비스(Flavis) 번호:
4.031
NACRES:
NA.21
감각 수용성의:
camphoraceous; woody; spicy
Grade:
FG
Fragrance grade
Halal
Kosher
생물학적 소스:
synthetic
Agency:
follows IFRA guidelines
meets purity specifications of JECFA
식품 알레르기항원:
no known allergens

생물학적 소스

synthetic

Quality Level

Grade

FG
Fragrance grade
Halal
Kosher

Agency

follows IFRA guidelines
meets purity specifications of JECFA

규정 준수

EU Regulation 1223/2009
EU Regulation 1334/2008 & 178/2002
FCC
FDA 21 CFR 117
FDA 21 CFR 172.515

분석

≥98%

refractive index

n20/D 1.522 (lit.)

bp

236-237 °C (lit.)

mp

3-4 °C (lit.)

density

0.976 g/mL at 20 °C (lit.)

응용 분야

flavors and fragrances

문건

see Safety & Documentation for available documents

식품 알레르기항원

no known allergens

향수 알레르기항원

no known allergens

감각 수용성의

camphoraceous; woody; spicy

SMILES string

CC(C)c1ccc(C)c(O)c1

InChI

1S/C10H14O/c1-7(2)9-5-4-8(3)10(11)6-9/h4-7,11H,1-3H3

InChI key

RECUKUPTGUEGMW-UHFFFAOYSA-N

유전자 정보

human ... UGT1A4(54657)

유사한 제품을 찾으십니까? 방문 제품 비교 안내

일반 설명

Carvacrol is a monoterpene compound that can be used as a flavoring agent in food and cosmetics. It is one of the major volatile components in oregano essential oil.

애플리케이션


  • Carvacrol and Thymol Hybrids: Potential Anticancer and Antibacterial Therapeutics.: This review explores the synthesis, characterization, and biological activities of carvacrol and thymol hybrids, highlighting their potential as anticancer and antibacterial agents. The study emphasizes the significance of these compounds in developing novel therapeutic strategies (Peter et al., 2024).

  • Essential Oil Constituents as Anti-Inflammatory and Neuroprotective Agents: An Insight through Microglia Modulation.: This review investigates the role of essential oil constituents, including carvacrol, in modulating microglial activity. The findings suggest significant anti-inflammatory and neuroprotective effects, providing insights into their potential therapeutic applications in neuroinflammatory diseases (Stojanović et al., 2024).

  • Evidence of the Protective Role of Carvacrol in a Retinal Degeneration Animal Model.: This study demonstrates the protective effects of carvacrol in a retinal degeneration model. The results indicate that carvacrol can mitigate retinal damage and preserve retinal function, suggesting its potential as a therapeutic agent for retinal diseases (Inda et al., 2024).


면책조항

The product is not intended for use as a biocide under global biocide regulations, including but not limited to US EPA′s Federal Insecticide Fungicide and Rodenticide Act, European Biocidal Products Regulation, Canada’s Pest Management Regulatory Agency, Turkey’s Biocidal Products Regulation, Korea’s Consumer Chemical Products and Biocide Safety Management Act (K-BPR) and others.

픽토그램

CorrosionExclamation markEnvironment

신호어

Danger

유해 및 위험 성명서

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Dam. 1 - Skin Corr. 1B

Storage Class Code

8A - Combustible corrosive hazardous materials

WGK

WGK 3

Flash Point (°F)

>212.0 °F

Flash Point (°C)

> 100 °C

개인 보호 장비

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter


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시험 성적서(COA)

Lot/Batch Number

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문서 라이브러리 방문

이미 열람한 고객

The natural antimicrobial carvacrol inhibits Campylobacter jejuni motility and infection of epithelial cells
Van Alphen LB, et al
PLoS ONE, 7(9), e45343-e45343 (2012)
Antimicrobial activity of carvacrol: current progress and future prospectives
Nostro A & Papalia T
Recent Patents on Anti-Cancer Drug Discovery, 7(1), 28-35 (2012)
Wei-Zhe Liang et al.
Toxicology, 303, 152-161 (2012-11-14)
Carvacrol is one of the main substances of essential oil which triggers intracellular Ca(2+) mobilization and causes cytotoxicity in diverse cell models. However, the mechanism of carvacrol-induced Ca(2+) movement and cytotoxicity is not fully understood. This study examined the effect
Bo Tang et al.
Oncogene, 38(20), 3946-3961 (2019-01-30)
Although VPAC1 and its ligand vasoactive intestinal peptide (VIP) are important in gastrointestinal physiology, their involvements in progression of gastrointestinal tumor have not been explored. Here, we found that higher expression of VIP/VPAC1 was observed in gastric cancer compared to
Ademola Oladunjoye et al.
Poultry science, 92(5), 1357-1365 (2013-04-11)
In the present study, low concentrations of carvacrol (0.025 to 0.2%) and lauric arginate (LAE; 25 to 200 ppm) were tested at 4, 22, and 45°C in a broth model, and higher concentrations of carvacrol (0.1 to 5%) and LAE

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