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Merck
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주요 문서

810188P

Avanti

TopFluor TMR PI

Avanti Research - A Croda Brand 810188P, powder

동의어(들):

TopFluor TMR PI, 1-oleoyl-2-(6-((4,4-difluoro-1,3-dimethyl-5-(4-methoxyphenyl)-4-bora-3a,4a-diaza-s-indacene-2-propionyl)amino)hexanoyl)-sn-glycero-3-phosphoinositol (Ammonium salt)

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About This Item

CAS Number:
MDL number:
UNSPSC 코드:
12352211
NACRES:
NA.25

분석

>99% (TLC)

양식

powder

포장

pkg of 1 × 50 μg (with stopper and crimp cap (810188P-50ug))

제조업체/상표

Avanti Research - A Croda Brand 810188P

배송 상태

dry ice

저장 온도

−20°C

일반 설명

Phosphatidylinositol (PI) is commonly found in animal tissues and bacteria. PI is soluble in water and chloroform/methanol. TopFluor TMR PI is a tetramethylrhodamine (TMR)-labeled fluorescent phospholipid.

애플리케이션

TopFluor TMR PI has been used in fluorescence quenching of 1-palmitoyl-2-{12-[(7-nitro-2−1,3-benzoxadiazol-4-yl)amino]dodecanoyl}-sn-glycero-3-phosphatidylcholine (NBD PC) in ternary mixtures of 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphatidylcholine (POPC)/ 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphatidylethanolamine(POPE)/ soy l-α-phosphatidylinositol (PI) vesicles.

생화학적/생리학적 작용

TopFluor-labeled lipids have spectral properties similar to tetramethylrhodamine (TMR).

포장

2 mL Amber Serum Vial with Stopper and Crimp Cap (810188P-50ug)

법적 정보

Avanti Research is a trademark of Avanti Polar Lipids, LLC
TopFluor is a trademark of Avanti Polar Lipids, LLC

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

No data available

Flash Point (°C)

No data available


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문서 라이브러리 방문

Lipids of membranes: Chemistry, biological role and applications as drug carriers
Hatziantonioy S and Demetzos C
Studies in Natural Products Chemistry, 34, 173-202 (2008)
Reorganization of Ternary Lipid Mixtures of Nonphosphorylated Phosphatidylinositol Interacting with Angiomotin
Kimble-Hill, et al.
The Journal of Physical Chemistry B, 122(35), 8404-8415 (2018)
Yi Wen et al.
Biophysical journal, 114(11), 2630-2639 (2018-06-07)
Phosphatidylinositol 4,5-bisphosphate (PI(4,5)P2 or PIP2), is a key component of the inner leaflet of the plasma membrane in eukaryotic cells. In model membranes, PIP2 has been reported to form clusters, but whether these locally different conditions could give rise to
Ann C Kimble-Hill et al.
The journal of physical chemistry. B, 122(35), 8404-8415 (2018-06-08)
Phosphatidylinositol (PI) lipids are necessary for many cellular signaling pathways of membrane associated proteins, such as angiomotin (Amot). The Amot family regulates cellular polarity, growth, and migration. Given the low concentration of PI lipids in these membranes, it is likely

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