810207X
Avanti
NBD Sphingosine-1-Phosphate
Avanti Research™ - A Croda Brand 810207X
동의어(들):
omega(7-nitro-2-1,3-benzoxadiazol-4-yl)-D-erythro-sphingosine-1-phosphate:methanol:water (65:25:4)
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모든 사진(2)
About This Item
실험식(Hill 표기법):
C24H40N5O8P
CAS Number:
Molecular Weight:
557.58
MDL number:
UNSPSC 코드:
12352211
NACRES:
NA.25
추천 제품
분석
>99% (TLC)
양식
liquid
포장
pkg of 1 × 1 mL (810207X-100ug)
pkg of 1 × 1 mL (810207X-50ug)
제조업체/상표
Avanti Research™ - A Croda Brand 810207X
농도
0.05 mg/mL (810207X-50ug)
0.1 mg/mL (810207X-100ug)
배송 상태
dry ice
저장 온도
−20°C
일반 설명
Sphingosine-1-phosphate is a phosphorylated sphingosine analog and is polar. It is terminally labelled by fluorescent nitrobenzo-2-oxa-1,3-diazole (NBD) group. Sphingosine-1-phosphate is abundantly stored in platelets.
애플리케이션
NBD sphingosine-1-phosphate has been used as a substrate in the detection of sphingosine-1-phosphate phosphatases (SPPase) enzymatic activity by in vitro assay.
생화학적/생리학적 작용
Sphingosine-1-phosphate (S1P) initiates DNA synthesis. It is also involved in cell division, cell growth and platelet activation. S1P mediates cell movement, differentiation and survival. It specifically stimulates endothelial cells.
포장
5 mL Amber Glass Screw Cap Vial (810207X-100ug)
5 mL Amber Glass Screw Cap Vial (810207X-50ug)
법적 정보
Avanti Research is a trademark of Avanti Polar Lipids, LLC
신호어
Danger
Hazard Classifications
Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Acute Tox. 4 Dermal - Carc. 2 - Eye Irrit. 2 - Flam. Liq. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 Oral - STOT SE 1 - STOT SE 3
표적 기관
Central nervous system
Storage Class Code
3 - Flammable liquids
WGK
WGK 3
가장 최신 버전 중 하나를 선택하세요:
Synthesis of fluorescence-labeled sphingosine and sphingosine 1-phosphate; effective tools for sphingosine and sphingosine 1-phosphate behavior
Hakogi T, et al.
Bioorganic & Medicinal Chemistry Letters, 13(4), 661-664 (2003)
Sphingosine-1-phosphate phosphatase 2 regulates pancreatic islet beta-cell endoplasmic reticulum stress and proliferation
Taguchi Y, et al.
The Journal of Biological Chemistry, 291(23), 12029-12038 (2016)
Lack of sphingosine 1-phosphate-degrading enzymes in erythrocytes
Ito K, et al.
Biochemical and biophysical research communications, 357(1), 212-217 (2007)
Gaelen S Smith et al.
Biomolecules, 3(3), 351-368 (2014-03-13)
Sphingosine-1-phosphate (S1P) is a bioactive sphingolipid that activates a family of G protein coupled-receptors (GPCRs) implicated in mammalian development, angiogenesis, immunity and tissue regeneration. S1P functions as a trophic factor for many cell types, including embryonic stem cells (ESCs). Sphingosine
Sphingosine 1-phosphate lyase, a key regulator of sphingosine 1-phosphate signaling and function.
Serra M and Saba JD
Advances in Enzyme Regulation, 50(1), 349-362 (2010)
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