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Merck
모든 사진(1)

주요 문서

810209P

Avanti

C6-NBD Ceramide

Avanti Research - A Croda Brand

동의어(들):

N-[6-[(7-nitro-2-1,3-benzoxadiazol-4-yl)amino]hexanoyl]-D-erythro-sphingosine

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About This Item

실험식(Hill 표기법):
C30H49N5O6
CAS Number:
Molecular Weight:
575.74
MDL number:
UNSPSC 코드:
12352211
NACRES:
NA.25

분석

>99% (TLC)

양식

powder

포장

pkg of 1 × 1 mg (810209P-1mg)

제조업체/상표

Avanti Research - A Croda Brand

배송 상태

dry ice

저장 온도

−20°C

SMILES string

[N+](=O)([O-])c1c2n[o]nc2c(cc1)NCCCCCC(=O)N[C@H]([C@H](O)\C=C\CCCCCCCCCCCCC)CO

InChI

1S/C30H49N5O6/c1-2-3-4-5-6-7-8-9-10-11-12-13-15-18-27(37)25(23-36)32-28(38)19-16-14-17-22-31-24-20-21-26(35(39)40)30-29(24)33-41-34-30/h15,18,20-21,25,27,31,36-37H,2-14,16-17,19,22-23H2,1H3,(H,32,38)/b18-15+/t25-,27+/m0/s1

InChI key

HZIRBXILQRLFIK-VPZZKNKNSA-N

일반 설명

C6-NBD ceramide is a fluorescent labelled compound, known to be useful for the detection of enzymatic action. C6-NBD ceramide is preferred over radioactive compounds.

애플리케이션

C6-NBD Ceramide is suitable as a substrate for sphingomyelin synthase activity assay.

생화학적/생리학적 작용

Ceramide is one of the products of sphingolipid metabolism. The members of ceramide synthases family are responsible for its synthesis. Each ceramide synthesized differs in its acyl chain length. Ceramides possess a wide range of functions, associated with apoptosis, cancer inhibition and chemotherapy. Its action is also related to neurodegenerative diseases.

포장

5 mL Amber Glass Screw Cap Vial (810209P-1mg)

법적 정보

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Storage Class Code

11 - Combustible Solids


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시험 성적서(COA)

Lot/Batch Number

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문서 라이브러리 방문

Handbook of Glycosyltransferases and Related Genes, 5-5 (2011)
A role for ceramides, but not sphingomyelins, as antagonists of insulin signaling and mitochondrial metabolism in C2C12 myotubes
Park M, et al.
The Journal of Biological Chemistry, 291(46), 23978-23988 (2016)
Mammalian ceramide synthases
Levy M and Futerman AH
IUBMB Life, 62(5), 347-356 (2010)

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