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Merck
모든 사진(3)

문서

840032C

Avanti

Brain PS

Avanti Research - A Croda Brand

동의어(들):

L-α-phosphatidylserine (Brain, Porcine) (sodium salt)

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About This Item

CAS Number:
UNSPSC 코드:
12352211
NACRES:
NA.25

분석

>99% (TLC)

형태

liquid

포장

pkg of 1 × 1 mL (840032C-10mg)
pkg of 1 × 2.5 mL (840032C-25mg)
pkg of 1 × 4 mL (840032C-100mg)

제조업체/상표

Avanti Research - A Croda Brand

농도

10 mg/mL (840032C-10mg)
10 mg/mL (840032C-25mg)
25 mg/mL (840032C-100mg)

지질 유형

phosphoglycerides

배송 상태

dry ice

저장 온도

−20°C

SMILES string

[H][C@@](COP([O-])(OC[C@](C([O-])=O)([H])[NH3+])=O)(OC(CCCCCCC/C=C\CCCCCCCC)=O)COC(CCCCCCCCCCCCCCCCC)=O.[Na+]

InChI

1S/C42H80NO10P.Na/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-31-33-40(44)50-35-38(36-51-54(48,49)52-37-39(43)42(46)47)53-41(45)34-32-30-28-26-24-22-20-18-16-14-12-10-8-6-4-2;/h18,20,38-39H,3-17,19,21-37,43H2,1-2H3,(H,46,47)(H,48,49);/q;+1/p-1/b20-18-;/t38-,39+;/m1./s1

InChI key

ALPKKMIPHGSQRX-NJZWBUMZSA-M

일반 설명

Phosphatidylserine (PS) is a natural phospholipid nutrient, which is located in the brain, lungs, heart, liver and skeletal muscle. It is an important component of the cell membrane.

애플리케이션

Brain PS has also been used in protein-lipid overlay (PLO) assay to evaluate the binding of SEIPIN to phosphatidic acid (PA).

생화학적/생리학적 작용

Phosphatidylserine (PS) regulates the activity of receptors, ion channels, enzymes and signaling molecules. It is implicated in monitoring membrane fluidity. PS plays a vital role in apoptosis and blood clotting.

포장

5 mL Clear Glass Sealed Ampule (840032C-100mg)
5 mL Clear Glass Sealed Ampule (840032C-10mg)
5 mL Clear Glass Sealed Ampule (840032C-25mg)

법적 정보

Avanti Research is a trademark of Avanti Polar Lipids, LLC

픽토그램

Skull and crossbonesHealth hazard

신호어

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

표적 기관

Central nervous system, Liver,Kidney

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


시험 성적서(COA)

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문서 라이브러리 방문

M Gangal et al.
Proceedings of the National Academy of Sciences of the United States of America, 96(22), 12394-12399 (1999-10-27)
Although the catalytic (C) subunit of cAMP-dependent protein kinase is N-myristylated, it is a soluble protein, and no physiological role has been identified for its myristyl moiety. To determine whether the interaction of the two regulatory (R) subunit isoforms (R(I)
Sensing phosphatidylserine in cellular membranes
Kay JG and Grinstein S
Sensors, 11(2) (2011)
Human SEIPIN binds anionic phospholipids
Yan R, et al.
Developmental Cell, 47(2), 248-256 (2018)
The effects of phosphatidylserine on endocrine response to moderate intensity exercise
Starks MA, et al.
Journal of the International Society of Sports Nutrition, 5(1), 11-11 (2008)
Gillian L Dornan et al.
Structure (London, England : 1993), 28(2), 145-156 (2019-12-14)
The class I phosphoinositide 3-kinases (PI3Ks) are key signaling enzymes composed of a heterodimer of a p110 catalytic subunit and a p85 regulatory subunit, with PI3K mutations being causative of multiple human diseases including cancer, primary immunodeficiencies, and developmental disorders.

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