추천 제품
분석
99% (TLC)
형태
powder
제조업체/상표
Avanti Research™ - A Croda Brand
배송 상태
dry ice
저장 온도
−20°C
일반 설명
Bicelle kit contains 200mg of dimyristoylphosphatidylcholine (DMPC), 200mg of dimyristoylphosphatidylglycerol (DMPG), 1g of 3-[(3-cholamidopropyl)-dimethylammonio]-1-propane sulfonate (CHAPS) and 1g of 3-(cholamidopropyl)dimethylammonio-2-hydroxy-1-propane-sulfonate (CHAPSO). Bicelle is a discoidal lipid aggregate. A bicelle consists of a planar bilayer at the center made of long-chain phospholipids, which are encircled by a detergent layer. The planar bilayer is generally composed of DMPC, which may have phospholipids such as (DMPG) for alteration of charge of the membrane. The detergent layer is composed of bile salt derivative, such as CHAPSO.
The bicelle kit is designed to aid with the production of high-quality membrane protein crystals. Bicelles can be integrated into standard crystallization protocols, and in contrast to micelles, bicelles maintain the protein in a more native bilayer environment allowing proteins to be captured in a more biologically relevant orientation.
생화학적/생리학적 작용
Bicelles acts as membrane mimetics and facilitate membrane-associated biomolecules study.
포장
20ML Clear Glass Screw Cap Vial for each component (850563P-1EA)
Package contains 200MG of DMPC, 200MG of DMPG, 1G of CHAPS, and 1G of CHAPSO
법적 정보
Avanti Research is a trademark of Avanti Polar Lipids, LLC
신호어
Warning
유해 및 위험 성명서
예방조치 성명서
Hazard Classifications
Acute Tox. 4 Oral
Storage Class Code
10 - Combustible liquids
WGK
WGK 3
시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.
Crystallization of Membrane Proteins in Bicelles
Methods in Molecular Biology, 914 (2012)
Biophysical journal, 81(4), 2163-2171 (2001-09-22)
Several complementary physical techniques have been used to characterize the aggregate structures formed in solutions containing dimyristoylphosphatidylcholine (DMPC)/dihexanoylphosphatidylcholine (DHPC) at ratios of < or =0.5 and to establish their morphology and lipid organization as that of bicelles. (31)P NMR studies
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