B-071

Baclofen solution

500 μg/mL (90:10 MeOH:DMSO), certified reference material, ampule of 1 mL, Cerilliant^®

• 동의어(들): Baclofen reference solution
• 실험식(Hill 표기법): C₁₀H₁₂ClNO₂
• Molecular Weight: 213.66
• MDL number: MFCD00055143
• UNSPSC 코드: 41116107
• NACRES: NA.24

속성

• Grade: certified reference material
• Quality Level: 300
• 양식: liquid
• 특징: Snap-N-Spike^®/Snap-N-Shoot^®
• 포장: ampule of 1 mL
• 제조업체/상표: Cerilliant^®
• 농도: 500 μg/mL (90:10 MeOH:DMSO)
• 기술: gas chromatography (GC): suitable; liquid chromatography (LC): suitable
• 응용 분야: clinical testing
• 형식: single component solution
• 저장 온도: −20°C
• SMILES string: NCC(CC(O)=O)c1ccc(Cl)cc1
• InChI: 1S/C10H12ClNO2/c11-9-3-1-7(2-4-9)8(6-12)5-10(13)14/h1-4,8H,5-6,12H2,(H,13,14)
• InChI key: KPYSYYIEGFHWSV-UHFFFAOYSA-N
• 유전자 정보: human ... GABBR1(2550) , GABBR2(9568)

설명

일반 설명

A certified solution standard for use in LC/MS or GC/MS applications in clinical toxicology, forensic analysis, pharmaceutical research or diagnostic testing. Baclofen, a derivative of gamma-aminobutyric acid (GABA), is a muscle relaxant used to treat spasticity. Marketed with brand names such as Kemstro, Lioresal or Gablofen, the drug has also shown effectiveness in the treatment of alcoholism. Discontinuation of baclofen can be associated with a withdrawal syndrome resembling benzodiazepine or alcohol withdrawal.

애플리케이션

<ul>
<li><strong>Baclofen solution for GABA receptor research:</strong> A nanosuspension-based microneedle skin patch of baclofen has been developed for the sustained management of multiple sclerosis-related spasticity, indicating potential applications of baclofen solution in neuropharmacology and muscle relaxation studies (Verana et al., 2023).</li>
<li><strong>High-purity baclofen liquid for biochemical studies:</strong> A retrospective study compared the effectiveness of baclofen with buprenorphine in managing acute opioid withdrawal, underscoring the clinical relevance and application of high-purity baclofen solution in therapeutic settings (Hermenau et al., 2023).</li>
</ul>

법적 정보

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany

Snap-N-Shoot is a registered trademark of Cerilliant Corporation

Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

안전성 정보

• 픽토그램: GHS02,GHS06,GHS08
• 신호어: Danger
• 유해 및 위험 성명서: H225,H301 + H311 + H331,H370
• 예방조치 성명서: P210 - P280 - P301 + P310 + P330 - P302 + P352 + P312 - P304 + P340 + P311
• Hazard Classifications: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1
• 표적 기관: Eyes
• Storage Class Code: 3 - Flammable liquids
• WGK: WGK 2
• Flash Point (°F): 49.5 °F - closed cup
• Flash Point (°C): 9.7 °C - closed cup