M-020

S(+)-Methamphetamine solution

1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant^®

• 동의어(들): dextro-Methamphetamine
• 실험식(Hill 표기법): C₁₀H₁₅N
• CAS Number: 537-46-2
• Molecular Weight: 149.23
• MDL number: MFCD00079140
• UNSPSC 코드: 41116107
• PubChem Substance ID: 329817739
• NACRES: NA.24

속성

• Grade: certified reference material
• Quality Level: 300
• 형태: liquid
• 특징: Snap-N-Spike^®/Snap-N-Shoot^®
• 포장: ampule of 1 mL
• 제조업체/상표: Cerilliant^®
• drug control: Narcotic Licence Schedule A (Switzerland); psicótropo (Spain); Decreto Lei 15/93: Tabela IIB (Portugal)
• 농도: 1.0 mg/mL in methanol
• 기술: gas chromatography (GC): suitable; liquid chromatography (LC): suitable
• 응용 분야: forensics and toxicology
• 형식: single component solution
• 저장 온도: 2-8°C
• SMILES string: CN[C@@H](C)Cc1ccccc1
• InChI: 1S/C10H15N/c1-9(11-2)8-10-6-4-3-5-7-10/h3-7,9,11H,8H2,1-2H3/t9-/m0/s1
• InChI key: MYWUZJCMWCOHBA-VIFPVBQESA-N
• 유전자 정보: human ... SLC6A2(6530) , SLC6A3(6531) , SLC6A4(6532)

설명

일반 설명

Methamphetamine is a psychostimulant drug of the phenethylamine and amphetamine classes. Known by the street names "meth," "ice," and "glass", this Snap-N-Spike^® reference solution is applicable for use in LC/MS or GC/MS applications including clinical toxicology, sports testing, forensic analysis, or urine drug testing. The dextrorotatory isomer of methamphetamine is sold under the trade name Desoxyn^® for treatment of ADHD and obesity.

애플리케이션

• Pharmacokinetic Studies of S(+)-Methamphetamine: A comprehensive study assessing the pharmacokinetic profile of S(+)-Methamphetamine highlighted its rapid absorption and metabolism, offering critical insights into its therapeutic potential and challenges in drug abuse scenarios. This research aids in optimizing dosing regimens and understanding the drug′s behavior in biological systems, essential for both clinical applications and forensic investigations (Rushton et al., 2024).


• Pharmaceutical Applications of S(+)-Methamphetamine: Research on S(+)-Methamphetamine′s role in neurochemical processes explored its effects on neurotransmitter systems, particularly focusing on its potential therapeutic applications for attention deficit hyperactivity disorder (ADHD) and weight loss. Studies like these inform drug design and repurposing strategies, helping to mitigate abuse risks while harnessing pharmacological benefits (Pardo et al., 2024).


• Drug Metabolism and Enantiomeric Analysis: Investigations into the metabolism of S(+)-Methamphetamine have provided detailed insights into its biotransformation pathways, crucial for developing antidotes and treatment strategies for overdose cases. This research also enhances the understanding of enantiomeric differences in drug activity, supporting the development of more targeted and effective therapeutic agents (Liut et al., 2024).


• Clinical Trials and Neurological Research: Systematic reviews of clinical trials involving S(+)-Methamphetamine have elucidated its complex pharmacodynamics and associated behavioral effects. This information is vital for neuroscientists and pharmacologists working to develop safer and more effective CNS stimulants with fewer side effects and lower abuse potential (Barkholtz et al., 2023).

법적 정보

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany

Desoxyn is a registered trademark of Abbott Laboratories Corp.

Snap-N-Shoot is a registered trademark of Cerilliant Corporation

Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

안전성 정보

• 픽토그램: GHS02,GHS06,GHS08
• 신호어: Danger
• 유해 및 위험 성명서: H225,H301 + H311 + H331,H370
• 예방조치 성명서: P210 - P280 - P301 + P310 + P330 - P302 + P352 + P312 - P304 + P340 + P311
• Hazard Classifications: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1
• 표적 기관: Eyes
• Storage Class Code: 3 - Flammable liquids
• WGK: WGK 1
• Flash Point (°F): 49.5 °F - closed cup
• Flash Point (°C): 9.7 °C - closed cup