N-902

Nortriptyline-D₃ hydrochloride solution

100 μg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant^®

• 실험식(Hill 표기법): C₁₉D₃H₁₈N · HCl
• CAS Number: 136765-48-5
• Molecular Weight: 302.86
• MDL number: MFCD00198172
• UNSPSC 코드: 41116107
• PubChem Substance ID: 329818692
• NACRES: NA.24

속성

• Grade: certified reference material
• Quality Level: 300
• 양식: liquid
• 특징: Snap-N-Spike^®/Snap-N-Shoot^®
• 포장: ampule of 1 mL
• 제조업체/상표: Cerilliant^®
• 농도: 100 μg/mL in methanol (as free base)
• 기술: gas chromatography (GC): suitable; liquid chromatography (LC): suitable
• 응용 분야: clinical testing
• 형식: single component solution
• 저장 온도: −20°C
• SMILES string: [2H]C([2H])([2H])NCCC=C1C2=C(C=CC=C2)CCC3=C1C=CC=C3.[H]Cl
• InChI: 1S/C19H21N.ClH/c1-20-14-6-11-19-17-9-4-2-7-15(17)12-13-16-8-3-5-10-18(16)19;/h2-5,7-11,20H,6,12-14H2,1H3;1H/i1D3;
• InChI key: SHAYBENGXDALFF-NIIDSAIPSA-N

설명

일반 설명

Nortriptyline is a second generation tricyclic antidepressant (TCA) marketed under trade names such as Sensoval, Aventyl^®, and Pamelor^® for treatment of major depression. Nortriptyline is also an active metabolite of the TCA amitriptyline. This certified Snap-N-Spike^® Solution is suitable as an internal standard for quantitation of nortriptyline levels by LC/MS or GC/MS in clinical toxicology, forensic analysis, urine drug testing, isotope dilution methods, or medication monitoring applications.

애플리케이션

• Quantification of Tricyclic Antidepressants in Serum Using Liquid Chromatography Electrospray Tandem Mass Spectrometry (HPLC-ESI-MS/MS).: This study demonstrates a robust method for the quantification of tricyclic antidepressants, including Nortriptyline-D3, using high-performance liquid chromatography coupled with electrospray ionization tandem mass spectrometry. The approach offers precise measurement essential for pharmacokinetic and neuropharmacological research, aligning with the interests of researchers in pharma and biotech focused on antidepressant metabolism studies (Clarke et al., 2016).

법적 정보

Aventyl is a registered trademark of Eli Lilly and Co.

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany

Pamelor is a registered trademark of Mallinckrodt Inc.

Snap-N-Shoot is a registered trademark of Cerilliant Corporation

Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

안전성 정보

• 픽토그램: GHS02,GHS06,GHS08
• 신호어: Danger
• 유해 및 위험 성명서: H225,H301 + H311 + H331,H370
• 예방조치 성명서: P210 - P280 - P301 + P310 + P330 - P302 + P352 + P312 - P304 + P340 + P311
• Hazard Classifications: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1
• 표적 기관: Eyes
• Storage Class Code: 3 - Flammable liquids
• WGK: WGK 2
• Flash Point (°F): 49.5 °F - closed cup
• Flash Point (°C): 9.7 °C - closed cup