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Merck
모든 사진(1)

주요 문서

04-004

Sigma-Aldrich

Anti-SOCS3 Antibody, clone 1B2

clone 1B2, Upstate®, from mouse

동의어(들):

suppressor of cytokine signaling 3, ATOD4, CIS3, Cish3, MGC71791, SOCS-3, SSI-3, SSI3

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About This Item

UNSPSC 코드:
12352203
eCl@ss:
32160702
NACRES:
NA.41

생물학적 소스

mouse

Quality Level

항체 형태

purified immunoglobulin

항체 생산 유형

primary antibodies

클론

1B2, monoclonal

종 반응성

mouse, human

제조업체/상표

Upstate®

기술

western blot: suitable

동형

IgG1

NCBI 수납 번호

UniProt 수납 번호

배송 상태

dry ice

타겟 번역 후 변형

unmodified

유전자 정보

human ... SOCS3(9021)

특이성

Recognizes SOCS3.

면역원

mouse SOCS3 recombinant GST fusion protein encompassing amino acids 2-44.

애플리케이션

Research Sub Category
Neuroregenerative Medicine

Developmental Neuroscience
This Anti-SOCS3 Antibody, clone 1B2 is validated for use in WB for the detection of SOCS3.

품질

Routinely evaluated by immunoblot.

표적 설명

25 kDa

물리적 형태

Format: Purified
Protein G Purified mouse monoclonal IgG in a solution of 50% glycerol, 0.02 M Phosphate buffer, pH 7.6, 0.25 M NaCl, 0.1% sodium azide as a preservative.

기타 정보

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

법적 정보

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

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Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 2

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


시험 성적서(COA)

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문서 라이브러리 방문

Daniel J Ham et al.
American journal of physiology. Endocrinology and metabolism, 310(11), E970-E981 (2016-04-21)
Amino acids, especially leucine, potently stimulate protein synthesis and reduce protein breakdown in healthy skeletal muscle and as a result have received considerable attention as potential treatments for muscle wasting. However, the normal anabolic response to amino acids is impaired
Evdokia Dimitriadis et al.
Endocrinology, 147(8), 3809-3817 (2006-05-20)
The differentiation of endometrial stromal cells into decidual cells (decidualization) is critical for embryo implantation, but the mechanisms remain poorly defined. Numerous paracrine agents including IL-11 promote human endometrial stromal cell (HESC) decidualization. IL-11 signaling is transduced by the signal
Sam Ansari et al.
Scientific data, 3, 150077-150077 (2016-01-06)
Smoking of combustible cigarettes has a major impact on human health. Using a systems toxicology approach in a model of chronic obstructive pulmonary disease (C57BL/6 mice), we assessed the health consequences in mice of an aerosol derived from a prototype
Tal Ben-Zvi et al.
Journal of cell science, 119(Pt 2), 380-387 (2006-01-18)
Fibroblast growth factor receptor (FGFR) signaling is transduced by the mitogen-activated protein kinase (MAPK) cascade and the signal transducers and activators of transcription (STATs). Suppressors of cytokine signaling (SOCS) proteins are expressed in response to cytokine-inducible stimulation of STAT phosphorylation
Kate D Sutherland et al.
Oncogene, 23(46), 7726-7733 (2004-09-14)
Suppressor of cytokine signaling (SOCS) proteins have emerged as critical attenuators of cytokine-mediated processes, suggesting a role in the suppression of tumorigenesis. In the ovary and mammary gland, cytokines such as prolactin and IL-6 are important regulators of growth and

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