04-135

Anti-Brachyury Antibody, clone 3E4.2

clone 3E4.2, Upstate^®, from mouse

• 동의어(들): T brachyury (mouse) homolog, T brachyury-like, T protein, T, brachyury homolog (mouse), transcription factor T
• UNSPSC 코드: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

속성

• 생물학적 소스: mouse
• Quality Level: 100
• 항체 형태: purified immunoglobulin
• 항체 생산 유형: primary antibodies
• 클론: 3E4.2, monoclonal
• 종 반응성: human
• 제조업체/상표: Upstate^®
• 기술: western blot: suitable
• 입력: sample type mesenchymal stem cell(s)
• 동형: IgG1κ
• NCBI 수납 번호: NP_003172
• UniProt 수납 번호: O15178
• 배송 상태: wet ice
• 타겟 번역 후 변형: unmodified
• 유전자 정보: human ... TBXT(6862)

설명

일반 설명

The Brachyury protein is a T-box transcription factor that is one of the earliest indicators of mesoderm formation during embryonic development. As the brachyury protein family is essential for the formation of the posterior body in all vertebrates, Brachyury has been shown to be expressed during gastrula and neurula stages, as well as in the developing notochord. Consequently, when mutations occur within the brachyury gene, severe vertebral malformations have been found to occur, as a direct result. In addition, current findings also indicate that the dysregulation of brachyury may also be linked to the formation of chordomas, which are malignant tumors that develop along the spine.

특이성

Reactivity with other species has not been tested.

This monoclonal antibody recognizes the brachyury protein.

면역원

Epitope: C-terminus

Synthetic human brachyury peptide, a.a. 224-435.

애플리케이션

Research Category
Stem Cell Research

Research Sub Category
Mesenchymal Stem Cells

This Anti-Brachyury Antibody, clone 3E4.2 is validated for use in WB for the detection of Brachyury.

품질

Routinely evaluated by Western blot on NT2 cell lysates.

Western Blotting:
Recommended working dilutions are 1:1000.

표적 설명

47 kDa

물리적 형태

Format: Purified

Protein G Purified

Purified mouse monoclonal IgG1κ in buffer containing PBS with 0.05% sodium azide.

저장 및 안정성

Maintain refrigerated at 2-8°C in undiluted aliquots for up to 12 months. Avoid repeat freeze/thaw cycles.

기타 정보

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

법적 정보

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

안전성 정보

• Storage Class Code: 12 - Non Combustible Liquids
• WGK: WGK 1
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable