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Merck
모든 사진(1)

Key Documents

07-625

Sigma-Aldrich

Anti-ATRIP Antibody

Upstate®, from rabbit

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모든 사진(1)

About This Item

UNSPSC 코드:
12352203
eCl@ss:
32160702
NACRES:
NA.41

생물학적 소스

rabbit

Quality Level

100

항체 형태

purified immunoglobulin

항체 생산 유형

primary antibodies

클론

polyclonal

종 반응성

human

제조업체/상표

Upstate®

기술

immunocytochemistry: suitable
western blot: suitable

동형

IgG

GenBank 수납 번호

AF451323

UniProt 수납 번호

Q8WXE1

배송 상태

wet ice

타겟 번역 후 변형

unmodified

유전자 정보

human ... ATRIP(84126)

관련 카테고리

일반 설명

Antibody recognizing ATR-Interacting Protein

특이성

ATRIP

면역원

GST fusion protein corresponding to residues 1-181 of human ATR interacting protein (ATRIP)

애플리케이션

Detect ATRIP with Anti-ATRIP Antibody (Rabbit Polyclonal Antibody), that has been shown to work in WB, ICC.
Research Category
Epigenetics & Nuclear Function
Research Sub Category
Cell Cycle, DNA Replication & Repair

품질

Routinely evaluated by immunoblot on modified RIPA lysates from HEK293, HeLa and U20S cells

표적 설명

85kDa

물리적 형태

70% storage buffer (0.05M Tris-glycine, 0.025M sodium phosphate, pH 7.4, 0.15M NaCl, 0.035% sodium azide) and 30% glycerol
Format: Purified
Protein G Purified

저장 및 안정성

2 years at -20°C

법적 정보

GenBank is a registered trademark of United States Department of Health and Human Services
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

10 - Combustible liquids

WGK

WGK 1

시험 성적서(COA)

제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.

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문서 라이브러리 방문

D Cortez et al.
Science (New York, N.Y.), 294(5547), 1713-1716 (2001-11-27)
The checkpoint kinases ATM (ataxia telangiectasia mutated) and ATR (ATM and Rad3 related) transduce genomic stress signals to halt cell cycle progression and promote DNA repair. We report the identification of an ATR-interacting protein (ATRIP) that is phosphorylated by ATR
Lee Zou et al.
Science (New York, N.Y.), 300(5625), 1542-1548 (2003-06-07)
The function of the ATR (ataxia-telangiectasia mutated- and Rad3-related)-ATRIP (ATR-interacting protein) protein kinase complex is crucial for the cellular response to replication stress and DNA damage. Here, we show that replication protein A (RPA), a protein complex that associates with
Qiang Li et al.
PloS one, 5(10), e13732-e13732 (2010-11-10)
H3K9 trimethylation (H3K9me3) and binding of PcG repressor complex-1 (PRC1) may play crucial roles in the epigenetic silencing of the p16 gene. However, the mechanism of the initiation of this trimethylation is unknown. In the present study, we found that
Janna Luessing et al.
iScience, 25(7), 104536-104536 (2022-06-28)
Abscission, the final stage of cytokinesis, occurs when the cytoplasmic canal connecting two emerging daughter cells is severed either side of a large proteinaceous structure, the midbody. Here, we expand the functions of ATR to include a cell-cycle-specific role in
Richard O Adeyemi et al.
Journal of virology, 88(17), 10189-10199 (2014-06-27)
The ATR kinase has essential functions in maintenance of genome integrity in response to replication stress. ATR is recruited to RPA-coated single-stranded DNA at DNA damage sites via its interacting partner, ATRIP, which binds to the large subunit of RPA.

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