218840

Caspase-8 Inhibitor II

InSolution

• 동의어(들): InSolution Caspase-8 Inhibitor II, Granzyme B Inhibitor III; Z-IE(OMe)TD(OMe)-FMK
• 실험식(Hill 표기법): C₃₀H₄₃FN₄O₁₁
• Molecular Weight: 654.68
• UNSPSC 코드: 12352200
• NACRES: NA.54

속성

• Quality Level: 100
• 양식: liquid
• 제조업체/상표: Calbiochem^®
• 저장 조건: OK to freeze; desiccated (hygroscopic); protect from light
• 배송 상태: wet ice
• 저장 온도: −20°C

설명

일반 설명

A 5 mM (250 µg/76 µl) solution of Z-IETD-FMK (Cat. No. 218759) in DMSO. Z-IETD-FMK is a potent, cell-permeable, and irreversible inhibitor of caspase-8 (MACH, FLICE, Mch5). Also inhibits granzyme B.

생화학적/생리학적 작용

Cell permeable: yes

Primary Target
caspase-8

Product does not compete with ATP.

Reversible: no

포장

Packaged under inert gas

경고

Toxicity: Irritant (B)

서열

Z-Ile-Glu(OMe)-Thr-Asp(OMe)-CH₂F*

물리적 형태

A 5 mM (250 µg/76 µl) solution of Z-IETD-FMK (Cat. No. 218759) in DMSO.

재구성

Following initial thaw, aliquot and freeze (-20°C).

분석 메모

≥98% (HPLC)

기타 정보

Martin, D.A., et al. 1998. J. Biol. Chem.273, 4345.
Sweeney, E.A., et al. 1998. FEBS Lett.425, 61.

법적 정보

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

안전성 정보

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 1
• Flash Point (°F): 188.6 °F - (refers to pure substance)
• Flash Point (°C): 87 °C - (refers to pure substance)