219385

Cathepsin B Inhibitor II

The Cathepsin B Inhibitor II controls the biological activity of Cathepsin B. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.

• 동의어(들): Cathepsin B Inhibitor II, Ac-LVK-CHO
• 실험식(Hill 표기법): C₁₉H₃₆N₄O₄
• Molecular Weight: 384.51
• UNSPSC 코드: 12352200
• NACRES: NA.77

속성

• Quality Level: 100
• 분석: ≥95% (HPLC)
• 양식: solid
• 제조업체/상표: Calbiochem^®
• 저장 조건: OK to freeze
• 색상: white
• solubility: water: 1 mg/mL
• 배송 상태: ambient
• 저장 온도: −70°C

설명

일반 설명

A more active lysinal analog of Leupeptin (Cat. No. 108975). A more potent inhibitor of cathepsin B (IC₅₀ = 4 nM) compared to leupeptin (IC₅₀ = 310 nM).

Lysinal analog of Leupeptin (Cat. No. 108975). A more potent inhibitor of cathepsin B (IC₅₀ = 4 nM) than of leupeptin (IC₅₀ = 310 nM). Note: this peptide forms cyclic isomers.

Note: this peptide forms cyclic isomers.

생화학적/생리학적 작용

Cell permeable: no

Primary Target
cathepsin B

Product does not compete with ATP.

Reversible: no

Target IC₅₀: 4 nM against cathepsin B

경고

Toxicity: Standard Handling (A)

서열

Ac-Leu-Val-lysinal

재구성

Following reconstitution aliquot and freeze (-70°C). Stock solutions are stable for up to 1 month at -70°C.

기타 정보

McConnell, R.M., et al. 1993. J. Med. Chem. 36, 1084.

법적 정보

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 1
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable