5.06135

Venlafaxine Hydrochloride

• 동의어(들): Venlafaxine Hydrochloride, SERT/NET Inhibitor, Venlafaxine, Serotonin-norepinephrine Inhibitor, Venlafaxien
• 실험식(Hill 표기법): C₁₇H₂₇NO₂ · xHCl
• CAS Number: 99300-78-4
• Molecular Weight: 277.40 (free base basis)
• MDL number: MFCD03658865
• UNSPSC 코드: 12352200
• NACRES: NA.77

속성

• 분석: ≥99% (HPLC)
• Quality Level: 100
• 양식: solid
• 효능: 82 nM K_i
• 제조업체/상표: Calbiochem^®
• 저장 조건: OK to freeze; protect from light
• 색상: white
• solubility: water: 100 mM; DMSO: 50 mM
• 저장 온도: 2-8°C
• SMILES string: [Cl-].N(CC(C2(CCCCC2)O)c1ccc(cc1)OC)(C)C.[H+]
• InChI: 1S/C17H27NO2.ClH/c1-18(2)13-16(17(19)11-5-4-6-12-17)14-7-9-15(20-3)10-8-14;/h7-10,16,19H,4-6,11-13H2,1-3H3;1H
• InChI key: QYRYFNHXARDNFZ-UHFFFAOYSA-N

설명

일반 설명

A dual reuptake inhibitor of serotonin-norepinephrine with strong preference to serotonin (K_i = 82 and 2480 nM for SERT and NET respectively). Also inhibits reuptake of dopamine. Used in studies of depression, ADHD, and stress-related anxiety.

생화학적/생리학적 작용

Primary Target
SERT/NET

포장

Packaged under inert gas

경고

Toxicity: Standard Handling (A)

기타 정보

Kaur, J., et al. et al. 2010. J. Pharmacy & Bioallied Sci.2, 22.

Aboelwafa, A., et al. 2010. AAPS PharmSciTech.11, 1026.
Bernardi, S., et al. 2009. J. Thermal Analysis & Calorimetry.97, 729.

법적 정보

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

안전성 정보

• 픽토그램: GHS09
• 유해 및 위험 성명서: H411
• 예방조치 성명서: P273 - P391 - P501
• Hazard Classifications: Aquatic Chronic 2
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable