8.40124

Span^® 85

for synthesis

• 동의어(들): Span^® 85, Sorbitan trioleate, (Z,Z,Z)-Sorbitan tri-9-octadecenoate
• 실험식(Hill 표기법): C₆₀H₁₀₈O₈
• CAS Number: 26266-58-0
• Molecular Weight: 957.49
• MDL number: MFCD00133820
• UNSPSC 코드: 12352108
• EC 인덱스 번호: 247-569-3
• NACRES: NA.22

속성

• vapor pressure: <1.4 hPa ( 20 °C)
• Quality Level: 200
• 형태: liquid
• 효능: 39800 mg/kg LD₅₀, oral (Rat)
• kinematic viscosity: 120 cSt(40 °C)
• 전이 온도: flash point 225 °C
• solubility: insoluble <0.001 g/L
• density: 0.95 g/cm³ at 20 °C
• 저장 온도: 2-30°C
• InChI: 1S/C60H108O8/c1-4-7-10-13-16-19-22-25-28-31-34-37-40-43-46-49-56(62)65-53-55(67-57(63)50-47-44-41-38-35-32-29-26-23-20-17-14-11-8-5-2)60-59(54(61)52-66-60)68-58(64)51-48-45-42-39-36-33-30-27-24-21-18-15-12-9-6-3/h25-30,54-55,59-61H,4-24,31-53H2,1-3H3/b28-25-,29-26-,30-27-/t54-,55?,59+,60-/m1/s1
• InChI key: PRXRUNOAOLTIEF-XDTJCZEISA-N

설명

애플리케이션

• Macromolecular Stabilization: Span^® 85 is used as a stabilizer for the preparation of PMMA colloidal particles in nonpolar media, proving effective in maintaining stability under various conditions, crucial for industrial applications in coatings and advanced materials manufacturing (Liu et al., 2022).


• Enhanced Nanoemulsion Systems: It plays a critical role in the formation of aerosolized nanoemulsion systems encapsulating docetaxel and curcumin, utilized in cancer therapy to improve therapeutic outcomes through enhanced drug delivery mechanisms (Abdul Rahman et al., 2020).


• Skin Protection Formulations: Span^® 85 is integral in the formulation and clinical assessment of microemulsion-based hydrogels for UV protection, demonstrating its utility in skincare products by enhancing sun protection factor and skin compatibility (Ebrahimi et al., 2019).


• Transdermal Drug Delivery: This surfactant is utilized in tailoring novel soft nano-vesicles, known as ′Flexosomes′, to enhance transdermal drug delivery, which is pivotal for non-invasive therapeutic applications and improving patient compliance (Mansour et al., 2019).

분석 메모

Hydroxyl value: 55 - 75
Saponification value: 170 - 190
Identity (IR): passes test
Due to its specific melting range the product may be solid, liquid, a solidified melt or a supercooled melt.

법적 정보

Span is a registered trademark of Croda International PLC

안전성 정보

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 1
• Flash Point (°F): 437.0 °F
• Flash Point (°C): 225 °C