8.51028

Bis-Boc-amino-oxyacetic acid

Novabiochem^®

• 동의어(들): Bis-Boc-amino-oxyacetic acid, Boc ₂-Aoa-OH
• 실험식(Hill 표기법): C₁₂H₂₁NO₇ · xH₂O
• Molecular Weight: 291.30 (anhydrous basis)
• UNSPSC 코드: 12352209
• NACRES: NA.22

속성

• Quality Level: 200
• 제품 라인: Novabiochem^®
• 분석: ≥97% (TLC)
• 형태: powder
• 반응 적합성: reagent type: ligand
• 제조업체/상표: Novabiochem^®
• 응용 분야: peptide synthesis
• 저장 온도: 2-8°C

설명

일반 설명

This reagent can be used to introduce a hydroxylamine functionality to N-terminal or side-chain amino groups. Hydroxylamine-labeled peptides prepared in this manner can be ligated in aqueous solution at pH 3.5 to aldehyde-containing peptides via oxime formation. This bis-protected derivative eliminates oligomer formation which can occur with mono-protected hydroxylamine reagents as a result of double acylation. Coupling of this derivative should be done using an OSu ester.

Literature references

^[1] J. C. Spetzler & T. Hoeg-Jensen (2001) J. Peptide Sci., 7, 537.

결합

Replaces: 01-63-0129

분석 메모

Colour (visual): white to slight yellow to beige
Appearance of substance (visual): powder
Identity (IR): passes test
Purity (TLC(CMA2)): ≥ 97 %
Water (K. F.): 3.0 - 8.0 %

To see the solvent systems used for TLC of Novabiochem^® products please click here.

법적 정보

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3