추천 제품
생물학적 소스
rabbit
Quality Level
항체 형태
affinity purified immunoglobulin
항체 생산 유형
primary antibodies
클론
polyclonal
정제법
affinity chromatography
종 반응성
human, rat, mouse
제조업체/상표
Chemicon®
기술
immunohistochemistry: suitable
동형
IgG
NCBI 수납 번호
UniProt 수납 번호
배송 상태
dry ice
타겟 번역 후 변형
unmodified
유전자 정보
human ... NEUROG3(50674)
일반 설명
Neurogenins are a family of bHLH transcription factors involved in specifying neuronal differentiation. They are related to Drosophila atonal. The neurogenins (ngns) make up one of these atonal-related gene families. In neural crest cells, the atonal-related neurogenin family is particularly important for the sensory lineage (Neurogenins Are Essential for the Formation of dorsal root ganglia), while the achaete-scute homologue ash1 (Mash1) is important for aspects of autonomic neurogenesis (Mash1 Is Essential for Noradrenergic Differentiation). Neurogenin-3 promotes pancreatic development.
특이성
Recognizes Neurogenin 3 (MATH4b), a Helix-loop-helix class of transcription factor.
면역원
Epitope: a.a. 80-93 of mouse Neurogenin 3.
Synthetic peptide, amino acids 80-93 of mouse Neurogenin 3.
애플리케이션
Anti-Neurogenin-3 Antibody, a.a. 80-93 of mouse Neurogenin-3. detects level of Neurogenin-3 & has been published & validated for use in IH.
Immunohistochemistry: 1:200-1:1,000.
Immunocytochemistry: Cat. # AB5684 detects Neurogenin-3 in PC12 cells at 1:500 dilution.
Not recommended for Western blot
Immunocytochemistry: Cat. # AB5684 detects Neurogenin-3 in PC12 cells at 1:500 dilution.
Not recommended for Western blot
Research Category
Neuroscience
Neuroscience
Research Sub Category
Developmental Neuroscience
Neuronal & Glial Markers
Developmental Neuroscience
Neuronal & Glial Markers
표적 설명
~ 23 kDa
물리적 형태
Affinity purified immunoglobulin. Precipitated antibody in a solution of 50% saturated ammonium sulfate and PBS containing no preservatives.
저장 및 안정성
Stable for 1 year at -20ºC from date of receipt.
분석 메모
Control
Rat brain tissue.
Rat brain tissue.
법적 정보
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
면책조항
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class Code
12 - Non Combustible Liquids
WGK
WGK 2
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.
Tzu-Lei Kuo et al.
iScience, 26(1), 105881-105881 (2023-01-20)
ARID1A is a tumor suppressor gene mutated in 7-10% of pancreatic cancer patients. However, its function in pancreas development and endocrine regulation is unclear. We generated mice that lack Arid1a expression in the pancreas. Our results showed that deletion of
Fang-Xu Jiang et al.
Stem cells (Dayton, Ohio), 35(5), 1341-1354 (2017-01-17)
Developmental stage-specific differentiation of stem or progenitor cells into safe and functional cells is of fundamental importance in regenerative medicine, including β-cell replacement. However, the differentiation of islet progenitor cells (IPCs) into insulin-secreting β cells remains elusive. Here, we report
Guido Carpino et al.
Stem cells (Dayton, Ohio), 34(5), 1332-1342 (2016-02-07)
Peribiliary glands (PBGs) are niches in the biliary tree and containing heterogeneous endodermal stem/progenitors cells that can differentiate, in vitro and in vivo, toward pancreatic islets. The aim of this study was to evaluate, in experimental and human diabetes, proliferation
Masayuki Shimoda et al.
Human gene therapy methods, 25(3), 206-219 (2014-05-23)
The generation of insulin-secreting cells from nonendocrine pancreatic epithelial cells (NEPEC) has been demonstrated for potential clinical use in the treatment of diabetes. However, previous methods either had limited efficacy or required viral vectors, which hinder clinical application. In this
Junping Wen et al.
Journal of diabetes, 9(7), 707-716 (2016-10-30)
β-Cells at different stages have different functions and capacity for proliferation, regenerative and apoptosis. The aim of the present study was to investigate whether there are changes in β-cell phonotype in the development of diabetes to identify potential β-cell targets
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