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Merck
모든 사진(1)

주요 문서

AB9042

Sigma-Aldrich

Anti-Brain Derived Neurotrophic Factor Antibody, pro

Chemicon®, from chicken

동의어(들):

proBDNF, pro BDNF

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About This Item

UNSPSC 코드:
12352203
eCl@ss:
32160702
NACRES:
NA.41

생물학적 소스

chicken

Quality Level

항체 형태

purified immunoglobulin

항체 생산 유형

primary antibodies

클론

polyclonal

종 반응성

mouse, rat, human

제조업체/상표

Chemicon®

기술

immunohistochemistry: suitable
immunoprecipitation (IP): suitable
western blot: suitable

UniProt 수납 번호

배송 상태

dry ice

타겟 번역 후 변형

unmodified

유전자 정보

human ... BDNF(627)

특이성

Reacts with proBDNF. Does not recognize mature BDNF isoforms.

면역원

Fusion protein from mouse proBDNF containing only the prodomain region.

애플리케이션

Anti-Brain Derived Neurotrophic Factor Antibody, pro detects level of Brain Derived Neurotrophic Factor & has been published & validated for use in IP, WB, IH.
Western blot: 1:500-1:1,000. Reacts with bands of 30 kD and 28 kD.Immunohistochemistry: 1:100-1:250 on frozen sections.

Immunohistochemistry: 1:100-1:200

Immunoprecipitation: 1:100

Optimal working dilutions must be determined by the end user.

물리적 형태

Chicken immunoglobulin. Liquid.
Format: Semi-Purified

법적 정보

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

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Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


시험 성적서(COA)

제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.

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문서 라이브러리 방문

Working memory deficits, increased anxiety-like traits, and seizure susceptibility in BDNF overexpressing mice.
Papaleo, F; Silverman, JL; Aney, J; Tian, Q; Barkan, CL; Chadman, KK; Crawley, JN
Learning & Memory null
Alta Berger et al.
Endocrinology, 157(2), 600-610 (2015-12-17)
In both mice and patients with Albright hereditary osteodystrophy, heterozygous inactivating mutations of Gsα, a ubiquitously expressed G protein that mediates receptor-stimulated intracellular cAMP production, lead to obesity and insulin resistance but only when the mutation is present on the
Heejung Chun et al.
Experimental neurobiology, 27(3), 155-170 (2018-07-20)
Astrocytes are the most abundant cell type in the brain and they make close contacts with neurons and blood vessels. They respond dynamically to various environmental stimuli and change their morphological and functional properties. Both physiological and pathological stimuli can
Beatrice Vignoli et al.
Communications biology, 4(1), 1152-1152 (2021-10-07)
Memory consolidation requires astrocytic microdomains for protein recycling; but whether this lays a mechanistic foundation for long-term information storage remains enigmatic. Here we demonstrate that persistent synaptic strengthening invited astrocytic microdomains to convert initially internalized (pro)-brain-derived neurotrophic factor (proBDNF) into
Matteo Bergami et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 33(28), 11464-11478 (2013-07-12)
In the adult rodent brain, the olfactory bulb (OB) is continuously supplied with new neurons which survival critically depends on their successful integration into pre-existing networks. Yet, the extracellular signals that determine the selection which neurons will be ultimately incorporated

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