추천 제품
생물학적 소스
rabbit
Quality Level
항체 형태
serum
항체 생산 유형
primary antibodies
클론
polyclonal
종 반응성
mouse, rat, human
기술
western blot: suitable
NCBI 수납 번호
UniProt 수납 번호
배송 상태
wet ice
타겟 번역 후 변형
unmodified
유전자 정보
human ... PEX13(5194)
일반 설명
Peroxisomal membrane protein 13 (PEX13) is a component of the peroxisomal translocation machinery, which binds to peroxisomal targeting signal receptors via its SH3 domain, and facilitates the import of these receptors into the peroxisome membrane. Defects in PEX13 have been linked to neurodegenerative disorders, such as Zellweger syndrome.
면역원
Recombinant protein corresponding to human PEX13 (peroxisomal membrane marker 13).
애플리케이션
Research Category
Inflammation & Immunology
Inflammation & Immunology
Research Sub Category
Inflammation & Autoimmune Mechanisms
Inflammation & Autoimmune Mechanisms
This Anti-PEX13 (peroxisomal membrane marker) Antibody is validated for use in Western Blotting, ICC for the detection of PEX13 (peroxisomal membrane marker).
품질
Evaluated by Western Blot in HepG2 cell lysate.
Western Blot Analysis: A 1:1,000 dilution of this antibody detected PEX13 (peroxisomal membrane marker) in HepG2 cell lysate.
Western Blot Analysis: A 1:1,000 dilution of this antibody detected PEX13 (peroxisomal membrane marker) in HepG2 cell lysate.
표적 설명
~49 kDa observed. This protein has an expected molecular weight of 44 kDa; however, it has been observed at ~49 kDa (Muller, C. C., et al. 2011. Dis Model Mech. 4(1):104-110.). An uncharacterized band may be observed at ~41 kDa in some cell lysates.
물리적 형태
Rabbit polyclonal serum with 0.05% sodium azide.
Unpurified
저장 및 안정성
Stable for 1 year at -20°C from date of receipt.
Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
분석 메모
Control
HepG2 cell lysate
HepG2 cell lysate
면책조항
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class Code
10 - Combustible liquids
WGK
WGK 1
시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.
Lysosomal exocytosis releases pathogenic α-synuclein species from neurons in synucleinopathy models.
Ying Xue Xie et al.
Nature communications, 13(1), 4918-4918 (2022-08-23)
Considerable evidence supports the release of pathogenic aggregates of the neuronal protein α-Synuclein (αSyn) into the extracellular space. While this release is proposed to instigate the neuron-to-neuron transmission and spread of αSyn pathology in synucleinopathies including Parkinson's disease, the molecular-cellular
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