추천 제품
생물학적 소스
mouse
Quality Level
결합
FITC conjugate
항체 형태
purified immunoglobulin
항체 생산 유형
primary antibodies
클론
HUTS-4, monoclonal
종 반응성
human
제조업체/상표
Milli-Mark®
기술
flow cytometry: suitable
동형
IgG2b
NCBI 수납 번호
UniProt 수납 번호
배송 상태
wet ice
타겟 번역 후 변형
unmodified
유전자 정보
human ... ITGB1(3688)
일반 설명
Integrin beta 1, also known as CD29, is a 130 kDa transmembrane glycoprotein that forms noncovalent complexes with various Integrin alpha subunits 1 to 6 (CD49a to CD49f) also known as Very Late Antigens (VLA). CD29 is also called platelet GPIIa. The antigen mediates cellular adhesion and has broad cellular reactivity, but is not expressed by erythrocytes. In normal peripheral blood it is found on a subset of CD4+ and CD8+ T lymphocytes and on a minority of B lymphocytes. The "inducer" subpopulation of CD4+ lymphocytes co-express CD4 and CD29.
애플리케이션
Milli-Mark Anti-Integrin β1-FITC Antibody, activated, clone HUTS-4 is an antibody against Integrin β1 for use in FC.
품질
Evaluated by flow cytometry using A431 cells.
표적 설명
88 kDa Calculated
기타 정보
Unconjugated antibody Cat. No. MAB2079Z is known to react with Rat.
법적 정보
MILLI-MARK is a registered trademark of Merck KGaA, Darmstadt, Germany
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Storage Class Code
12 - Non Combustible Liquids
WGK
WGK 2
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.
J Meller et al.
Journal of thrombosis and haemostasis : JTH, 10(7), 1397-1408 (2012-05-09)
Kindlin-3 is a novel integrin activator in hematopoietic cells, and its deficiency leads to immune problems and severe bleeding, known as leukocyte adhesion deficiency III (LAD-III). Our current understanding of Kindlin-3 function primarily relies on analysis of animal models or
Marleen Leidecker et al.
Microbiology spectrum, 11(3), e0388622-e0388622 (2023-03-31)
Invasion of host cells is an important feature of Staphylococcus aureus. The main internalization pathway involves binding of the bacteria to host cells, e.g., endothelial cells, via a fibronectin (Fn) bridge between S. aureus Fn binding proteins and α5β1-integrin, followed
Dwayne A L Vickers et al.
PloS one, 8(6), e65828-e65828 (2013-06-14)
Adhesion-based microfluidic cell separation has proven to be very useful in applications ranging from cancer diagnostics to tissue engineering. This process involves functionalizing microchannel surfaces with a capture molecule. High specificity and purity capture can be achieved using this method.
Dasom Shin et al.
Nature communications, 15(1), 2789-2789 (2024-03-31)
Proprotein convertase subtilisin/kexin type-9 (PCSK9) binds to and degrades low-density lipoprotein (LDL) receptor, leading to increase of LDL cholesterol in blood. Its blockers have emerged as promising therapeutics for cardiovascular diseases. Here we show that PCSK9 itself directly induces inflammation
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